ArticleJournal of psychopathology and behavioral assessment2018
Working memory mediates increased negative affect and suicidal ideation in childhood attention-deficit/hyperactivity disorder.
Article in Journal of psychopathology and behavioral assessment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence and Correlates of Suicide and Nonsuicidal Self-injury in Children: A Systematic Review and Meta-analysis.JAMA psychiatry · 2022Pooled it
- Negative Affectivity and Emotion Dysregulation as Mediators between ADHD and Disordered Eating: A Systematic Review.Nutrients · 2020Pooled it
- Trial
- Working memory associated with anti-suicidal ideation effect of repeated-dose intravenous ketamine in depressed patients.European archives of psychiatry and clinical neuroscience · 2021Trial
- Neurocognitive and Temperament Predictors of Changes in Child and Adolescent Suicidal Thoughts and Behaviors for Youths With and Without Attention-Deficit/Hyperactivity Disorder.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Dampened positive emotion and a PTSD diagnosis are related to suicidal thoughts and behavior in young children receiving intensive psychiatric care.Psychiatry research · 2025Article
- ADHD and Cannabis Use in College Students: Examining Indirect Effects of Coping Motives.Substance use & misuse · 2025Article
- Potential Mechanisms Underlying Suicidality in Autistic People with Attention Deficit/Hyperactivity Disorder: Testing Hypotheses from the Interpersonal Theory of Suicide.Autism in adulthood · 2024Article
- Systematic Review of the Link Between Social Cognition and Suicidal Ideation and Behavior in People With Serious Mental Illness.Schizophrenia bulletin open · 2024Review
- The Three-year Outcome of Emotional Symptoms in Clinically Referred Youth with ADHD and their Relationship to Neuropsychological Functions.Scandinavian journal of child and adolescent psychiatry and psychology · 2022Article
- Multimodal Neuroimaging of Suicidal Thoughts and Behaviors in a U.S. Population-Based Sample of School-Age Children.The American journal of psychiatry · 2021Article
- Correlations between Quality of Life, School Bullying, and Suicide in Adolescents with Attention-Deficit Hyperactivity Disorder.International journal of environmental research and public health · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveChildren with attention-deficit/hyperactivity disorder (ADHD) are at greater risk for suicidal ideation and suicide attempts compared to those without ADHD. Increased risk is at least partially attributable to a subset of children with ADHD and comorbid depression or disruptive behavior disorders; however, the early predictors and mechanisms driving increased risk are not well understood. Here, we investigate the contributions of two candidate mechanisms for increased suicidal ideation in children with ADHD: executive function and negative affect.
methods623 clinically well-characterized, community-recruited children classified by research criteria as ADHD (n=388) or typically-developing controls (n=253) participated. Parent-report on the Temperament in Middle Childhood Questionnaire provided a measure of negative affectivity. Children completed laboratory tasks to measure response inhibition and working memory. Suicidal ideation was evaluated by parent report during a semi-structured interview and child responses on the Children's Depression Inventory.
resultsCompared to typically developing controls, children with ADHD had higher rates of suicidal ideation, more negative affect, slower stop signal reaction times, and weaker working memory. Statistical path-model analyses confirmed the hypothesis that weaker working memory in ADHD statistically mediated increased negative affect. Weaker working memory also mediated and increased suicidal ideation in these cross sectional data. Findings were not attributable to comorbid disruptive behavioral disorders. Poor response inhibition did not reliably mediate negative affect or suicidal ideation.
conclusionImpairment in working memory is an important early risk factor for suicidal ideation in children with ADHD, and may help in identifying children for prevention and early intervention efforts.
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