ArticleScientific reports2018
Uranium (VI) detection in groundwater using a gold nanoparticle/paper-based lateral flow device.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 62 citations in OpenAlex.
- Heavy Metal Ion Detection Based on Lateral Flow Assay Technology: Principles and Applications.Biosensors · 2025Review
- Detection of radioactive ions: current status of nanomaterial-based sensors.Mikrochimica acta · 2025Review
- Gamma radiolytically synthesized phosphate decorated gold nanoparticles for ultra-trace level detection of U(VI) in water.Discover nano · 2025Article
- Machine learning in point-of-care testing: innovations, challenges, and opportunities.Nature communications · 2025Review
- Plasmonic nanoparticle sensors: current progress, challenges, and future prospects.Nanoscale horizons · 2024Review
- Lateral flow immunoassay for simultaneous detection of C. difficile, MRSA, and K. pneumoniae.Mikrochimica acta · 2024Article
- Mn-ferrite nanoparticles as promising magnetic tags for radiofrequency inductive detection and quantification in lateral flow assays.Nanoscale advances · 2024Article
- Automation for lateral flow rapid tests: Protocol for an open-source fluid handler and applications to dengue and African swine fever tests.PLOS global public health · 2024Article
- Aptamer-Based Point-of-Care Devices: Emerging Technologies and Integration of Computational Methods.Biosensors · 2023Review
- Article
- Toward Next Generation Lateral Flow Assays: Integration of Nanomaterials.Chemical reviews · 2022Review
- Yeast Surface Display Platform for Rapid Selection of an Antibody Library via Sequential Counter Antigen Flow Cytometry.Antibodies (Basel, Switzerland) · 2022Article
- Multiscale Modeling of Broadband Perfect Absorbers Based on Gold Metallic Molecules.ACS omega · 2022Article
- Review
- Tutorial: design and fabrication of nanoparticle-based lateral-flow immunoassays.Nature protocols · 2020Review
- Evaluation of the radiological quality of water released by a uranium mining in Brazil.Environmental science and pollution research international · 2020Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The contamination in groundwater due to the presence of uranium is nowadays a subject of concern due to the severe health problems associated with renal failure, genotoxicity and cancer. The standard methods to detect uranium require time-consuming processes and expensive non-portable equipment, so these measurements are rarely performed in-field, which increases the time until water samples are analysed. Furthermore, the few portable methods available do not allow quantitative analysis and the detection limit is often not low enough to reach the recommendations for drinking water (30 ppb or 126 nM of uranium). For the first time, we propose a portable, fast, inexpensive and sensitive paper-based biosensor able to detect in situ U(VI) in water samples: U(VI) selective gold nanoparticle-based lateral flow strips. Antibody-coated gold nanoparticles are used as labels in the proposed lateral flow system because of their biocompatibility; in addition, these nanoparticles provide high sensitivity due to their intense plasmonic effect. The antibody used in the assay recognizes soluble U(VI) complexed to the chelator, 2,9-dicarboxyl-1,10-phenanthroline (DCP). Because of the small size of the U(VI)-DCP complex, this assay employs a competitive format that reaches a limit of detection of 36.38 nM, lower than the action level (126 nM) established by the World Health Organization and the U.S. Environmental Protection Agency for drinking waters.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.