ArticleThe American journal of gastroenterology2018
To Screen or Not to Screen Adults 45-49 Years of Age: That is the Question.
Article in The American journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Trends in the epidemiology of young-onset colorectal cancer: a worldwide systematic review.BMC cancer · 2020Pooled it
- Early-onset colorectal cancer in Argentina: a multicenter surgical analysis of incidence, stage, and metastatic patterns.Lancet regional health. Americas · 2026Article
- Colorectal cancer molecular profiling: Opportunities for early detection.Clinical and translational medicine · 2025Review
- Insights from age-stratified endoscopic detection metrics support initiating colorectal cancer screening at age 45.BMC gastroenterology · 2025Article
- Review
- The Young: Early-Onset Colon Cancer.Clinics in colon and rectal surgery · 2025Review
- Prognostic Differences Between Early-Onset and Late-Onset Colorectal Cancer.Medicina (Kaunas, Lithuania) · 2025Article
- Early Onset Colorectal Cancer: Molecular Underpinnings Accelerating Occurrence.Cellular and molecular gastroenterology and hepatology · 2025Review
- Identifying Gaps in Early-Onset Colorectal Cancer Prevention, Screening, and Treatment in the Philippines.Annals of surgical oncology · 2024Article
- Serum ferritin and the risk of early-onset colorectal cancer.World journal of gastrointestinal oncology · 2024Article
- Ethnic disparities in early-onset colorectal cancer incidence, screening rates and risk factors prevalence in Guam.Preventive medicine reports · 2024Article
- Early-Onset Colorectal Cancer: Current Insights.Cancers · 2023Review
- Comparison of the short- and long-term prognosis of early-onset colorectal cancer compared with later-onset colorectal cancer: A systematic review and meta-analysis.Health science reports · 2023Article
- Molecular genetics of early-onset colorectal cancer.World journal of biological chemistry · 2023Review
- Early-onset colorectal cancer: A review of current knowledge.World journal of gastroenterology · 2023Review
- Mailed fecal testing and patient navigation versus usual care to improve rates of colorectal cancer screening and follow-up colonoscopy in rural Medicaid enrollees: a cluster-randomized controlled trial.Implementation science communications · 2022Article
- Early-onset colorectal cancer risk extends to second- and third-degree relatives.Cancer epidemiology · 2021Article
- Transcriptomic landscape of early age onset of colorectal cancer identifies novel genes and pathways in Indian CRC patients.Scientific reports · 2021Article
- Increasing Rates of Colorectal Cancer Among Young People in California, 1988-2017.Journal of registry management · 2021Article
- Colorectal cancer risk based on extended family history and body mass index.Genetic epidemiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Should we adopt the recently published American Cancer Society (ACS) recommendations to screen adults at 45 years of age? The main reasons for adopting the recommendation include the increase of colorectal cancer (CRC) in the young, especially late-stage tumors. Screening at 45 years is also supported by predictive modeling, which the ACS employed using updated and improved models as compared to those previously used by the United States Preventive Services Task Force. Reasons against adopting include concerns with the models as well as diversion of scarce screening resources away from high-risk populations. Readers are provided with opposing viewpoints regarding the ACS recommendation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.