Evidence map›Paper›PMID 30385831›Full record

SynthesisThe American journal of gastroenterology2018

Anxiety Associated with Colonoscopy and Flexible Sigmoidoscopy: A Systematic Review.

Chengyue Yang, Vaelan Sriranjan, Ahmed M Abou-Setta, William Poluha, John R Walker, Harminder Singh

3 registry-linked trialsOpen access · greenAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The American journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 71 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04628052 naterminatednot on this mapstarted 2020, after this paper: background citation

The Effect of Music on Colonoscopy (MUSICOL): A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of Illinois at ChicagoRan2020 to 2023Enrolled83ConditionsProcedural Anxiety, Colon PolypArmsColonoscopy
NCT04973878 naunknown statusnot on this mapstarted 2021, after this paper: background citation

The Optimal Sequence in Same-day Bidirectional Endoscopy Under Deep Anesthesia Induced by Propofol Combined With Fentanyl: A Prospective Randomized Controlled ,Two Centers Trial

TypeinterventionalSponsorRuijin HospitalRan2021 to 2022Enrolled544ConditionsBidirectional Endoscopy, Deep SedationArmsEGD first, Colonoscopy first
NCT07664800 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effect of Nurse-Delivered Online Counseling on Invasive Pain, Anxiety, and Comfort Levels in Patients Undergoing Colonoscopy

TypeinterventionalSponsorSanko UniversityRan2023 to 2023Enrolled60ConditionsColonoscopy (Procedure), 18 Years and Over, Literacy, No Communication DifficultiesArmsOnline Nursing Counseling
3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 2 syntheses or guidelines pooled it, 125 citations in OpenAlex.

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  6. A Video Decision Aid Decreases Fear of Colonoscopy After an Abnormal Fecal Immunochemical Test Result: A Pilot Study.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
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  13. The Effect of Virtual Reality on Pain and Anxiety During Colonoscopy: A Randomized Controlled Trial.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021
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  20. Effect of music therapy on patient experience in gastrointestinal endoscopy: a scoping review.Journal of the Canadian Association of Gastroenterology · 2026
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chengyue YangDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. Faculty of Science, University of Manitoba, Winnipeg, Manitoba, Canada. George and Fay Yee Centre for Healthcare Innovation, University of Manitoba, Winnipeg, Manitoba, Canada. Sciences and Technology Library, University of Manitoba, Winnipeg, Manitoba, Canada. Department of Clinical Health Psychology, University of Manitoba, Winnipeg, Manitoba, Canada.
Vaelan SriranjanDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. Faculty of Science, University of Manitoba, Winnipeg, Manitoba, Canada. George and Fay Yee Centre for Healthcare Innovation, University of Manitoba, Winnipeg, Manitoba, Canada. Sciences and Technology Library, University of Manitoba, Winnipeg, Manitoba, Canada. Department of Clinical Health Psychology, University of Manitoba, Winnipeg, Manitoba, Canada.
Ahmed M Abou-SettaDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. Faculty of Science, University of Manitoba, Winnipeg, Manitoba, Canada. George and Fay Yee Centre for Healthcare Innovation, University of Manitoba, Winnipeg, Manitoba, Canada. Sciences and Technology Library, University of Manitoba, Winnipeg, Manitoba, Canada. Department of Clinical Health Psychology, University of Manitoba, Winnipeg, Manitoba, Canada.
William PoluhaDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. Faculty of Science, University of Manitoba, Winnipeg, Manitoba, Canada. George and Fay Yee Centre for Healthcare Innovation, University of Manitoba, Winnipeg, Manitoba, Canada. Sciences and Technology Library, University of Manitoba, Winnipeg, Manitoba, Canada. Department of Clinical Health Psychology, University of Manitoba, Winnipeg, Manitoba, Canada.
John R WalkerDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. Faculty of Science, University of Manitoba, Winnipeg, Manitoba, Canada. George and Fay Yee Centre for Healthcare Innovation, University of Manitoba, Winnipeg, Manitoba, Canada. Sciences and Technology Library, University of Manitoba, Winnipeg, Manitoba, Canada. Department of Clinical Health Psychology, University of Manitoba, Winnipeg, Manitoba, Canada.
Harminder SinghDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. Faculty of Science, University of Manitoba, Winnipeg, Manitoba, Canada. George and Fay Yee Centre for Healthcare Innovation, University of Manitoba, Winnipeg, Manitoba, Canada. Sciences and Technology Library, University of Manitoba, Winnipeg, Manitoba, Canada. Department of Clinical Health Psychology, University of Manitoba, Winnipeg, Manitoba, Canada.
University of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAddressing procedure-related anxiety should improve adherence to colorectal cancer screening programs and diagnostic colonoscopy. We performed a systematic review to assess anxiety among individuals undergoing colonoscopy or flexible sigmoidoscopy (FS).

methodsWe searched multiple electronic databases for studies evaluating anxiety associated with colonoscopy or FS published from 2005 to 2017. Two reviewers independently identified studies, extracted data, and assessed study quality. The main outcomes were the magnitude of pre-procedure anxiety, types of concerns, predictors of anxiety, and effectiveness of anxiety-lowering interventions in individuals undergoing lower endoscopy. The protocol was prospectively registered in PROSPERO.

resultsFifty-eight studies (24,490 patients) met the inclusion criteria. Patients undergoing colonoscopy had a higher mean level of anxiety than that previously reported in the general population, with some studies reporting more than 50% of patients having moderate-to-severe anxiety. Areas of anxiety-related concern included bowel preparation, difficulties with the procedure (embarrassment, pain, possible complications, and sedation), and concerns about diagnosis; including fear of being diagnosed with cancer. Female gender, higher baseline anxiety, functional abdominal pain, lower education, and lower income were associated with greater anxiety prior to colonoscopy. Providing higher-quality information before colonoscopy, particularly with a video, shows promise as a way of reducing pre-procedure anxiety but the studies to date are of low quality.

conclusionsA large proportion of patients undergoing colonoscopy report anxiety before the procedure. Improvement in pre-procedure information delivery and evaluation of approaches to reduce anxiety is required, especially for those with predictors of pre-procedure anxiety.

Indexed as

AnxietyColonoscopyColorectal NeoplasmsEarly Detection of CancerHumansPatient Education as TopicPreoperative PeriodPrevalenceSeverity of Illness IndexSigmoidoscopy

Identifiers

PMID30385831
PMCPMC6768596
OpenAlexW2899119880

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.