ArticleThorax2019
Fas activation alters tight junction proteins in acute lung injury.
Open access · bronzeAbstract read
In one paragraph
Article in Thorax, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 54 citations in OpenAlex.
- Impaired Alveolar Barrier Integrity Exposes FGFR1 Orchestrating Tight Junction Homeostasis via Occludin Transcription Maintenance.International journal of biological sciences · 2026Article
- Alveolar Epithelial Cell Dysfunction in Acute Respiratory Distress Syndrome: Mechanistic Insights and Targeted Interventions.Biomedicines · 2025Review
- Bone morphogenetic protein 10 serves as a biomarker and a potential therapeutic target for endothelial dysfunction in endotoxin-induced acute lung injury.Journal of translational medicine · 2025Article
- Context-dependent roles of palmitoylation in acute respiratory distress syndrome: integrating inflammation, cell death and repair.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Effective Restoration of Gastric and Esophageal Tissues in an In Vitro Model of GERD: Mucoadhesive and Protective Properties of Xyloglucan, Pea Proteins, and Polyacrylic Acid.International journal of molecular sciences · 2025Article
- Consumption of Endogenous Caspase-3 Activates Molecular Theranostic Nanoplatform against Inflammation-Induced Profibrotic Positive Feedback in Pulmonary Fibrosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Esketamine Regulates Mitophagy through ULK1/FUNDC1 Signaling Pathway to Improve LPS-induced Acute Respiratory Distress Syndrome.Current pharmaceutical design · 2025Article
- Airway epithelium damage in acute respiratory distress syndrome.Critical care (London, England) · 2024Article
- Palmitoylethanolamide as a Supplement: The Importance of Dose-Dependent Effects for Improving Nervous Tissue Health in an In Vitro Model.International journal of molecular sciences · 2024Article
- Lactate Protects Intestinal Epithelial Barrier Function from Dextran Sulfate Sodium-Induced Damage by GPR81 Signaling.Nutrients · 2024Article
- CPT1A as a potential therapeutic target for lipopolysaccharide-induced acute lung injury in mice.Scientific reports · 2024Article
- Lysophosphatidylcholine 14:0 Alleviates Lipopolysaccharide-Induced Acute Lung Injury via Protecting Alveolar Epithelial Barrier by Activation of Nrf2/HO-1 Pathway.Journal of inflammation research · 2024Article
- Ferulic acid alleviates alveolar epithelial barrier dysfunction in sepsis-induced acute lung injury by activating the Nrf2/HO-1 pathway and inhibiting ferroptosis.Pharmaceutical biology · 2022Article
- Club cell protein (CC)16 as potential lung injury marker in a porcine 72 h polytrauma model.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Tight Junctions, the Epithelial Barrier, and Toll-like Receptor-4 During Lung Injury.Inflammation · 2022Review
- Sevoflurane Dampens Acute Pulmonary Inflammation via the Adenosine Receptor A2B and Heme Oxygenase-1.Cells · 2022Article
- Role of metalloproteases in the CD95 signaling pathways.Frontiers in immunology · 2022Review
- SARS-CoV-2 Infection Triggers Auto-Immune Response in ARDS.Frontiers in immunology · 2022Article
- Investigating the Intercellular Communication Network of Immune Cell in Acute Respiratory Distress Syndrome with Sepsis.Computational and mathematical methods in medicine · 2022Article
- Whole patient knowledge modeling of COVID-19 symptomatology reveals common molecular mechanisms.Frontiers in molecular medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 2 countries.
Raquel Herrero *CIBER de Enfermedades Respiratorias, Instituto de Investigación Carlos III, Madrid, Spain.ORCID 0000-0001-8789-0904
Lucia Prados *Laboratory of Biochemistry, Hospital Universitario de Getafe, Madrid, Spain.
Antonio FerrueloCIBER de Enfermedades Respiratorias, Instituto de Investigación Carlos III, Madrid, Spain.
Ferranda PuigCIBER de Enfermedades Respiratorias, Instituto de Investigación Carlos III, Madrid, Spain.
Rachele PandolfiDepartment of Pharmacology, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.
Raquel Guillamat-PratsCIBER de Enfermedades Respiratorias, Instituto de Investigación Carlos III, Madrid, Spain.ORCID 0000-0001-6960-0985
Laura MorenoCIBER de Enfermedades Respiratorias, Instituto de Investigación Carlos III, Madrid, Spain.ORCID 0000-0001-9028-2299
Gustavo Matute-BelloCenter for Lung Biology, Division of Pulmonary and Critical Care Medicine, Department of Medicine, and the Medical Research Service of the VA Puget Sound Healthcare System., University of Washington, Seattle, Washington, USA.
Antonio ArtigasCritical Care Center, Corporació Sanitària i Universitària Parc Taul, Institut d' Investigació i Innovació Parc Taulí, Barcelona, Spain.
Andres EstebanCIBER de Enfermedades Respiratorias, Instituto de Investigación Carlos III, Madrid, Spain.
José Ángel LorenteCIBER de Enfermedades Respiratorias, Instituto de Investigación Carlos III, Madrid, Spain.
Centro de Investigación Biomédica en Red · ESHospital Universitario de Getafe · ESUniversidad Complutense de Madrid · ESCorporació Sanitària Parc Taulí · ESUniversity of Washington · US
Funding
Inhibition of the Fas/FasL system in experimental acute lung injuryI01BX002914 · VA · VA PUGET SOUND HEALTHCARE SYSTEM · PI MATUTE-BELLO, GUSTAVO · 2016 to 2020
–BLRD VA I01 BX002914
Abstract
PubMed holds no abstract for this paper.
Indexed as
Alveolar Epithelial CellsAnimalsApoptosisBronchoalveolar Lavage FluidCaspase 3Caspase InhibitorsCell LineFas Ligand Proteinfas ReceptorHumansMaleMiceMice, Inbred C57BLOccludinPermeabilityProtein-Tyrosine KinasesCaspase 3Caspase InhibitorsFas Ligand ProteinFas protein, mousefas ReceptorOccludinOCLN protein, humanOcln protein, mouseProtein-Tyrosine KinasesRecombinant ProteinsTJP1 protein, humanTjp1 protein, mouseZonula Occludens-1 Proteinardsinnate immunitypulmonary oedema
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.