Evidence map›Paper›PMID 30385579›Full record

ArticleScience (New York, N.Y.)2018

Experimental evolution of a fungal pathogen into a gut symbiont.

Gloria Hoi Wan Tso, Jose Antonio Reales-Calderon, Alrina Shin Min Tan, XiaoHui Sem, Giang Thi Thu Le, Tze Guan Tan, Ghee Chuan Lai, K G Srinivasan, Marina Yurieva, Webber Liao and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Science (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 158 papers.

0numbers the graph read from it
0cells of the map it votes in
158citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

158 citing papers in PubMed.

  1. Article
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  5. Article
  6. Profound cell wall remodeling inMicrobiology spectrum · 2026
    Article
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  8. Article
  9. Article
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  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Commensal colonization ofMicrobiology spectrum · 2025
    Article
  18. Review
  19. Review
  20. Article

98 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Gloria Hoi Wan TsoSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove Immunos #04, Singapore 138648, Singapore.ORCID 0000-0003-3658-539X
Jose Antonio Reales-CalderonSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove Immunos #04, Singapore 138648, Singapore.
Alrina Shin Min TanSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove Immunos #04, Singapore 138648, Singapore.ORCID 0000-0002-4216-1262
XiaoHui SemSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove Immunos #04, Singapore 138648, Singapore.ORCID 0000-0002-4962-9825
Giang Thi Thu LeSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove Immunos #04, Singapore 138648, Singapore.
Tze Guan TanSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove Immunos #04, Singapore 138648, Singapore.
Ghee Chuan LaiSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove Immunos #04, Singapore 138648, Singapore.
K G SrinivasanSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove Immunos #04, Singapore 138648, Singapore.
Marina YurievaSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove Immunos #04, Singapore 138648, Singapore.ORCID 0000-0002-5761-0382
Webber LiaoSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove Immunos #04, Singapore 138648, Singapore.
Michael PoidingerSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove Immunos #04, Singapore 138648, Singapore.ORCID 0000-0002-1047-2277
Francesca ZolezziSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove Immunos #04, Singapore 138648, Singapore.
Giulia RancatiInstitute of Medical Biology, A*STAR, 8A Biomedical Grove, Immunos #05, Singapore 138648, Singapore.ORCID 0000-0003-0835-0139
Norman PavelkaSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove Immunos #04, Singapore 138648, Singapore. norman_pavelka@immunol.a-star.edu.ORCID 0000-0003-4542-9970

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbes live in symbiosis with their hosts, but how mutualistic animal-microbe interactions emerge is not understood. By adaptively evolving the opportunistic fungal pathogen

Indexed as

Adaptive ImmunityHost-Pathogen InteractionsAnimalsBiological EvolutionCandida albicansFungal ProteinsGastrointestinal MicrobiomeGastrointestinal TractMiceMice, Inbred C57BLMutationSymbiosisTranscription FactorsVirulence FactorsFungal ProteinsTranscription FactorsVirulence Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.