ArticleThe Journal of biological chemistry2018
The melanization road more traveled by: Precursor substrate effects on melanin synthesis in cell-free and fungal cell systems.
Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Polymorphic α-Glucans as Structural Scaffolds in Cryptococcus Cell Walls for Chitin, Capsule, and Melanin: Insights FromAngewandte Chemie (International ed. in English) · 2025Article
- Comparative analysis of polysaccharide and cell wall structure in Aspergillus nidulans and Aspergillus fumigatus by solid-state NMR.Carbohydrate polymers · 2025Article
- Elucidating structure and metabolism of insect biomaterials by solid-state NMR.Solid state nuclear magnetic resonance · 2024Review
- Comparative Analysis of Polysaccharide and Cell Wall Structure inbioRxiv : the preprint server for biology · 2024Article
- Polysaccharide assemblies in fungal and plant cell walls explored by solid-state NMR.Structure (London, England : 1993) · 2023Review
- Biomimetic pheomelanin to unravel the electronic, molecular and supramolecular structure of the natural product.Chemical science · 2023Article
- Fungi as a source of eumelanin: current understanding and prospects.Journal of industrial microbiology & biotechnology · 2023Article
- In Silico Characterization of the Physicochemical and Biological Properties of the Pink (Bioinformatics and biology insights · 2023Article
- Solid-State NMR Investigations of Extracellular Matrixes and Cell Walls of Algae, Bacteria, Fungi, and Plants.Chemical reviews · 2022Review
- Cryptococcus neoformans melanization incorporates multiple catecholamines to produce polytypic melanin.The Journal of biological chemistry · 2022Article
- Fungal Melanin and the Mammalian Immune System.Journal of fungi (Basel, Switzerland) · 2021Review
- Unconventional Constituents and Shared Molecular Architecture of the Melanized Cell Wall ofJournal of fungi (Basel, Switzerland) · 2020Article
- Tailoring NMR experiments for structural characterization of amorphous biological solids: A practical guide.Solid state nuclear magnetic resonance · 2020Review
- Zinc and Autophagy in Age-Related Macular Degeneration.International journal of molecular sciences · 2020Review
- Chemoenzymatic elaboration of the Raper-Mason pathway unravels the structural diversity within eumelanin pigments.Chemical science · 2020Article
- Biomolecular complex viewed by dynamic nuclear polarization solid-state NMR spectroscopy.Biochemical Society transactions · 2020Review
- Melanin deposition in twoThe Journal of biological chemistry · 2020Article
- The structural unit of melanin in the cell wall of the fungal pathogenThe Journal of biological chemistry · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 2 countries.
Funding
Abstract
Natural brown-black eumelanin pigments confer structural coloration in animals and potently block ionizing radiation and antifungal drugs. These functions also make them attractive for bioinspired materials design, including coating materials for drug-delivery vehicles, strengthening agents for adhesive hydrogel materials, and free-radical scavengers for soil remediation. Nonetheless, the molecular determinants of the melanin "developmental road traveled" and the resulting architectural features have remained uncertain because of the insoluble, heterogeneous, and amorphous characteristics of these complex polymeric assemblies. Here, we used 2D solid-state NMR, EPR, and dynamic nuclear polarization spectroscopic techniques, assisted in some instances by the use of isotopically enriched precursors, to address several open questions regarding the molecular structures and associated functions of eumelanin. Our findings uncovered: 1) that the identity of the available catecholamine precursor alters the structure of melanin pigments produced either in
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.