Evidence map›Paper›PMID 30385399›Full record

ArticleNew biotechnology2019

Effect of amino acids on transcription and translation of key genes in E. coli K and B grown at a steady state in minimal medium.

Antonino Baez, Amit Kumar, Ashish K Sharma, Eric D Anderson, Joseph Shiloach

Open access · greenAbstract read
In one paragraph

Article in New biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Antonino BaezLaboratorio de Ecología Molecular Microbiana, Centro de Investigaciones en Ciencias Microbiológicas, Instituto de Ciencias, Benemérita Universidad Autónoma de Puebla (BUAP), Puebla 72000, Mexico. Electronic address: antonino.baez@correo.buap.mx.
Amit KumarBiotechnology Core Laboratory, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Health, Bethesda, MD, 20892, United States.
Ashish K SharmaBiotechnology Core Laboratory, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Health, Bethesda, MD, 20892, United States.
Eric D AndersonMass Spectrometry Facility, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Health, Bethesda, MD, 20892, United States.
Joseph ShiloachBiotechnology Core Laboratory, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Health, Bethesda, MD, 20892, United States. Electronic address: josephs@niddk.nih.gov.
National Institute of Diabetes and Digestive and Kidney Diseases · USBenemérita Universidad Autónoma de Puebla · MX

Funding

Understanding metabolism and stress conditions of recombinant microorganismsZIADK075081 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI SHILOACH, JOSEPH · 2012 to 2022
$2.6M
Metabolism of recombinant E. coliZ01DK070009 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI SHILOACH, JOSEPH · 2007 to 2008
$568k
Intramural NIH HHS Z01 DK070009
6 · The paper itself

Abstract

Growing E. coli to high densities is a common strategy for biologicals production. The process is implemented by using complex or minimal media with different feeding strategies. To understand the effect of amino acids, E. coli B and K were grown at a steady state of 0.35 h

Indexed as

Genes, BacterialAmino AcidsBioreactorsCitric Acid CycleCulture MediaEscherichia coliGene Expression Regulation, BacterialGene OntologyProtein BiosynthesisProteomicsTranscription, GeneticTranscriptomeAmino AcidsCulture MediaChemostatEscherichia coliOverflow metabolismProteomeTranscriptome

Identifiers

PMID30385399
PMCPMC9554925
OpenAlexW2898959644

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.