Evidence map›Paper›PMID 30384833›Full record

ArticleBMC gastroenterology2018

Biologic treatment of Japanese patients with inflammatory bowel disease.

Jörg Mahlich, Katsuyoshi Matsuoka, Rosarin Sruamsiri

Abstract read
In one paragraph

Article in BMC gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trends in the use of biologic agents and their persistence rates in inflammatory bowel disease in India.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Optimal use of biologics with endoscopic balloon dilatation for repeated intestinal strictures in Crohn's disease.JGH open : an open access journal of gastroenterology and hepatology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jörg MahlichHealth Economics & Outcomes Research, Janssen, Johnson & Johnson Platz 1, 41470, Neuss, Germany. Joerg.mahlich@gmail.com.ORCID http://orcid.org/0000-0003-1110-2793
Katsuyoshi MatsuokaDepartment of Gastroenterology and Hepatology, Toho University Sakura Medical Center, Sakura, Japan.
Rosarin SruamsiriCenter of Pharmaceutical Outcomes Research, Naresuan University, Phitsanulok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is little information regarding the use of biologics in Inflammatory Bowel Disease (IBD) patients in Japan. The aim of this study was to determine the factors associated with the use of biologics in the treatment of Japanese patients with IBD.

methodsAn online survey was conducted among Japanese patients with IBD (n = 1035). Socioeconomic as well as treatment related information was collected. Logistic regression was applied to analyze the determinants of biologic treatment.

resultsYounger age (≤ 40 years vs. > 65 years; OR:0.24), time since diagnosis (< 2 years vs. < 15 years; OR: 4.16), surgical history (OR:1.98) and visiting university hospitals (university hospitals vs. clinics; OR: 0.47) were associated with biologic treatment for Japanese IBD patients.

conclusionsCurrently, biologics have been used in younger IBD patients which may give rise to the presence of an age bias in biologic treatment. Further studies are required to confirm these results and to define appropriate IBD patients who should be treated with biologic agent.

Indexed as

AdultAgedAge FactorsBiological ProductsComorbidityFemaleHospitals, UniversityHumansInflammatory Bowel DiseasesJapanMaleMiddle AgedSex FactorsSocioeconomic FactorsBiological ProductsBiologic treatmentIBDJapan

Identifiers

PMID30384833
PMCPMC6211510

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.