Evidence map›Paper›PMID 30384402›Full record

ArticleClinical endoscopy2018

Linked Color Imaging and Blue Laser Imaging for Upper Gastrointestinal Screening.

Hiroyuki Osawa, Yoshimasa Miura, Takahito Takezawa, Yuji Ino, Tsevelnorov Khurelbaatar, Yuichi Sagara, Alan Kawarai Lefor, Hironori Yamamoto

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 4 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 4 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Diagnostic performance of blue laser imaging for early detection of gastric cancer: A systematic review and meta-analysis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Pooled it
  3. Pooled it
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  5. Trial
  6. Trial
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  8. Review
  9. Review
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  12. Characteristics of Superficial Gastric Neoplasms Detected Not by White Light Imaging but by Linked Color Imaging.JGH open : an open access journal of gastroenterology and hepatology · 2025
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hiroyuki OsawaDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan.
Yoshimasa MiuraDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan.
Takahito TakezawaDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan.
Yuji InoDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan.
Tsevelnorov KhurelbaatarDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan.
Yuichi SagaraDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan.
Alan Kawarai LeforDepartment of Medicine, Department of Surgery, Jichi Medical University, Shimotsuke, Japan.
Hironori YamamotoDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan.
Jichi Medical University · JP

Funding

Fujifilm CorporationFujifilm Medical Corporation
6 · The paper itself

Abstract

White light imaging (WLI) may not reveal early upper gastrointestinal cancers. Linked color imaging (LCI) produces bright images in the distant view and is performed for the same screening indications as WLI. LCI and blue laser imaging (BLI) provide excellent visibility of gastric cancers in high color contrast with respect to the surrounding tissue. The characteristic purple and green color of metaplasias on LCI and BLI, respectively, serve to increase the contrast while visualizing gastric cancers regardless of a history of Helicobacter pylori eradication. LCI facilitates color-based recognition of early gastric cancers of all morphological types, including flat lesions or those in an H. pylori-negative normal background mucosa as well as the diagnosis of inflamed mucosae including erosions. LCI reveals changes in mucosal color before the appearance of morphological changes in various gastric lesions. BLI is superior to LCI in the detection of early esophageal cancers and abnormal findings of microstructure and microvasculature in close-up views of upper gastrointestinal cancers. Excellent images can also be obtained with transnasal endoscopy. Using a combination of these modalities allows one to obtain images useful for establishing a diagnosis. It is important to observe esophageal cancers (brown) using BLI and gastric cancers (orange) surrounded by intestinal metaplasia (purple) and duodenal cancers (orange) by LCI.

Indexed as

Blue laser imagingEarly gastric cancerLinked color imaging

Identifiers

PMID30384402
PMCPMC6283759
OpenAlexW2899172304

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.