Evidence map›Paper›PMID 30384127›Full record

ArticleBiomaterials2019

Fabrication of centimeter-scale and geometrically arbitrary vascular networks using in vitro self-assembly.

Joshua T Morgan, Jasmine Shirazi, Erica M Comber, Christian Eschenburg, Jason P Gleghorn

Abstract read
In one paragraph

Article in Biomaterials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
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  11. Technique for rapidly forming networks of microvessel-like structures.bioRxiv : the preprint server for biology · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Sex-related external factors influence pulmonary vascular angiogenesis in a sex-dependent manner.American journal of physiology. Heart and circulatory physiology · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joshua T MorganDepartment of Biomedical Engineering, University of Delaware, Newark, DE 19716, USA.
Jasmine ShiraziDepartment of Biomedical Engineering, University of Delaware, Newark, DE 19716, USA.
Erica M ComberDepartment of Biomedical Engineering, University of Delaware, Newark, DE 19716, USA.
Christian EschenburgDepartment of Biomedical Engineering, University of Delaware, Newark, DE 19716, USA.
Jason P GleghornDepartment of Biomedical Engineering, University of Delaware, Newark, DE 19716, USA. Electronic address: gleghorn@udel.edu.

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI Shawn W Polson · 2012 to 2026
$67.2M
Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Gregory E Hicks · 2013 to 2026
$60.5M
COBRE Center for Cancer Research DevelopmentP30GM110759 · NIGMS · RHODE ISLAND HOSPITAL · PI RAMRATNAM, BHARAT · 2015 to 2019
$6.3M
Pilot Research Subproject ProgramP30GM110758 · NIGMS · UNIVERSITY OF DELAWARE · PI POLENOVA, TATYANA · 2014 to 2018
$5.8M
Pressure in lung development and congenital diaphragmatic herniaR01HL133163 · NHLBI · UNIVERSITY OF DELAWARE · PI GLEGHORN, JASON PAUL · 2017 to 2021
$1.9M
Zeiss LSM710 Inverted Confocal MicroscopeS10OD016361 · OD · UNIVERSITY OF DELAWARE · PI CAPLAN, JEFFREY L · 2015 to 2015
$444k
Arsenic-mediated fibrosis and developmental dysregulation in the fetal lungR21ES027962 · NIEHS · UNIVERSITY OF DELAWARE · PI GLEGHORN, JASON PAUL · 2018 to 2019
$411k
NHLBI NIH HHS R01 HL133163NIEHS NIH HHS R21 ES027962NIGMS NIH HHS P20 GM103446NIGMS NIH HHS P30 GM110758NIGMS NIH HHS P30 GM110759NIGMS NIH HHS U54 GM104941NIH HHS S10 OD016361
6 · The paper itself

Abstract

One of the largest challenges facing the field of tissue engineering is the incorporation of a functional vasculature, allowing effective nourishment of graft tissue beyond diffusion length scales. Here, we demonstrate a methodology for inducing the robust self-assembly of endothelial cells into stable three-dimensional perfusable networks on millimeter and centimeter length scales. Utilizing broadly accessible cell strains and reagents, we have rigorously tested a state space of cell densities (0.5-2.0 × 10

Indexed as

Neovascularization, PhysiologicAnimalsBiocompatible MaterialsCollagenEndothelial CellsHumansHuman Umbilical Vein Endothelial CellsRatsTissue EngineeringTissue ScaffoldsBiocompatible MaterialsCollagenEndothelial cellMultiscalePerfusionSelf-assemblyTissue engineeringVasculogenesis

Identifiers

PMID30384127
PMCPMC6238648

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.