Evidence map›Paper›PMID 30383978›Full record

ArticleBiochemistry and cell biology = Biochimie et biologie cellulaire2019

Characterizing chloride-dependent acidification in brain clathrin-coated vesicles

Mary R Weston, Joseph A Mindell

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry and cell biology = Biochimie et biologie cellulaire, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mary R WestonMembrane Transport Biophysics Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
Joseph A MindellMembrane Transport Biophysics Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
National Institute of Neurological Disorders and Stroke · US

Funding

Chloride fluxes in organellar membranesZIANS003015 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI MINDELL, JOSEPH A · 2009 to 2025
$14.2M
Ion fluxes in lysosomal membranesZ01NS003015 · NINDS · NEUROLOGICAL DISORDERS AND STROKE · PI MINDELL, JOSEPH A · 2006 to 2008
$995k
Intramural NIH HHS Z01 NS003015
6 · The paper itself

Abstract

Endocytic organelles maintain their acidic pH using the V-type ATPase proton pump. However, proton accumulation across the membrane generates a voltage and requires the movement of an additional ion, known as a counterion, to dissipate charge buildup. The role of counterion movement in endosomes is not clear, but a subpopulation of early endosomes, clathrin-coated vesicles (CCVs), has previously been shown to use external chloride (Cl

Indexed as

AnimalsBrainCattleChloridesClathrin-Coated VesiclesHydrogen-Ion ConcentrationChloridesacidificationchloridechlorureendosomemembranetransport

Identifiers

PMID30383978
PMCPMC8404411
OpenAlexW2899235699

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.