Evidence map›Paper›PMID 30383816›Full record

ArticlePloS one2018

Prevalence of hyperuricemia and the relationship between serum uric acid and obesity: A study on Bangladeshi adults.

Nurshad Ali, Rasheda Perveen, Shahnaz Rahman, Shakil Mahmood, Sadaqur Rahman, Shiful Islam, Tangigul Haque, Abu Hasan Sumon, Rahanuma Raihanu Kathak, Noyan Hossain Molla and 5 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed, 2 pooled it
18.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

129 citing papers in PubMed, 2 syntheses or guidelines pooled it, 234 citations in OpenAlex.

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69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Nurshad AliDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh.ORCID 0000-0003-1649-0887
Rasheda PerveenDepartment of Biochemistry and Molecular Biology, Gonoshasthaya Samaj Vittik Medical College, Gono University, Savar, Dhaka, Bangladesh.
Shahnaz RahmanDepartment of Biochemistry and Molecular Biology, Gonoshasthaya Samaj Vittik Medical College, Gono University, Savar, Dhaka, Bangladesh.
Shakil MahmoodDepartment of Biochemistry and Molecular Biology, Gonoshasthaya Samaj Vittik Medical College, Gono University, Savar, Dhaka, Bangladesh.
Sadaqur RahmanDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
Shiful IslamDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh.ORCID 0000-0002-1826-6777
Tangigul HaqueDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
Abu Hasan SumonDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
Rahanuma Raihanu KathakDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
Noyan Hossain MollaDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
Farjana IslamDepartment of Biochemistry and Molecular Biology, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, Bangladesh.
Nayan Chandra MohantoDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
Shaikh Mirja NurunnabiDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
Shamim AhmedDepartment of Biochemistry and Molecular Biology, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
Mustafizur RahmanDepartment of Biochemistry and Molecular Biology, Gonoshasthaya Samaj Vittik Medical College, Gono University, Savar, Dhaka, Bangladesh.
Shahjalal University of Science and Technology · BDGono University · BDGopalganj Science and Technology University · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesRecent studies have shown that hyperuricemia is commonly associated with dyslipidemia, cardiovascular diseases, hypertension and metabolic syndrome. Elevated serum uric acid has been demonstrated to be associated with obesity in the adult population in many countries; however, there is still a lack of evidence for the Bangladeshi population. The aims of this study were to evaluate the prevalence of hyperuricemia and determine the relationship between serum uric acid (SUA) and obesity among the Bangladeshi adults.

methodsIn this cross-sectional study, blood samples were collected from 260 adults (142 males and 118 females) and analyzed for SUA and lipid profile. All participants were categorized as underweight (n = 11), normal (n = 66), overweight (n = 120) and obese (n = 63) according to the body mass index (BMI) scale for the Asian population. Based on SUA concentration the participants were stratified into four quartiles (Q1: < 232 μmol/L, Q2: 232-291 μmol/L, Q3: 292-345 μmol/L and Q4: > 345 μmol/L).

resultsThe mean age and BMI of the participants were 32.5 ± 13.3 years and 24.9 ± 3.8 kg/m2, respectively. The average level of SUA was 294 ± 90 μmol/L with a significant difference between males and females (p < 0.001). Overall, the estimated prevalence of hyperuricemia was 9.3% with 8.4% in male and 10.2% in female participants. There were significant increases in the prevalence of obesity (17.4%, 22.2%, 28.6% and 31.8%, respectively, p < 0.01 for trend) across the SUA quartiles. A multiple logistic regression analysis revealed that SUA quartiles were independently associated with the presence of obesity (p < 0.01).

conclusionPresent study indicates a significant positive relationship between SUA and obesity among the Bangladeshi adults. Therefore, routine measurement of SUA is recommended in obese individuals to prevent hyperuricemia and its related complications.

Indexed as

AdolescentAdultBangladeshCross-Sectional StudiesFemaleHumansHyperuricemiaMaleMiddle AgedObesityPrevalenceUric AcidYoung AdultUric Acid

Identifiers

PMID30383816
PMCPMC6211757
OpenAlexW2899372932

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.