Evidence map›Paper›PMID 30383806›Full record

ArticlePloS one2018

Predictors of adult outcomes in clinically- and legally-ascertained youth with externalizing problems.

Richard Border, Robin P Corley, Sandra A Brown, John K Hewitt, Christian J Hopfer, Michael C Stallings, Tamara L Wall, Susan E Young, Soo Hyun Rhee

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. A Shared Multivariate Brain-Behavior Relationship in a Transdiagnostic Sample of Adolescents.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Richard BorderInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, United States of America.ORCID 0000-0002-6293-2968
Robin P CorleyInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, United States of America.
Sandra A BrownDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, United States of America.
John K HewittInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, United States of America.
Christian J HopferInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, United States of America.
Michael C StallingsInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, United States of America.
Tamara L WallDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, United States of America.
Susan E YoungDepartment of Psychiatry, Anschutz Medical Campus, University of Colorado Denver, Aurora, CO, United States of America.
Soo Hyun RheeInstitute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, United States of America.
University of Colorado Boulder · USUniversity of California San Diego · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Twin StudyP60DA011015 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HEWITT, JOHN K. · 1997 to 2013
$22.5M
GENETICS OF ADOLESCENT ANTISOCIAL DRUG DEPENDENCER01DA012845 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HEWITT, JOHN K. · 2000 to 2012
$7.1M
Research Training: Mental Health Behavior GeneticsT32MH016880 · NIMH · UNIVERSITY OF COLORADO AT BOULDER · PI Naomi P. Friedman, Matthew Charles Keller · 1985 to 2026
$5.3M
Genetics and Progression of Early-onset Substance Dependence and HIV RiskR01DA035804 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HOPFER, CHRISTIAN J, STALLINGS, MICHAEL CRAIG · 2014 to 2018
$4.9M
Mentoring Clinical Investigators in Adolescent-onset Substance Use Disorders ResearchK24DA032555 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HOPFER, CHRISTIAN J · 2013 to 2022
$1.9M
Genetics of Adolescent Antisocial Drug DependenceR01DA021905 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WALL, TAMARA L · 2008 to 2012
$1.9M
NIDA NIH HHS K24 DA032555NIDA NIH HHS P60 DA011015NIDA NIH HHS R01 DA012845NIDA NIH HHS R01 DA021905NIDA NIH HHS R01 DA035804NIMH NIH HHS T32 MH016880
6 · The paper itself

Abstract

Externalizing problems (EP), including rule-breaking, aggression, and criminal involvement, are highly prevalent during adolescence, but the adult outcomes of adolescents exhibiting EP are characterized by heterogeneity. Although many youths' EP subside after adolescence, others' persists into adulthood. Characterizing the development of severe EP is essential to prevention and intervention efforts. Multiple predictors of adult antisocial personality disorder (ASPD) and legal outcomes of a large sample (N = 1205) of clinically- or legally-ascertained adolescents (ages 12-19 years) with severe EP were examined. Many psychosocial predictors hypothesized to predict persistence of EP demonstrated zero-order associations with adult outcomes, but accounted for little unique variation after accounting for baseline conduct disorder symptoms (CD) and demographic factors. Baseline measures of intelligence, which explained independent variation in legal outcomes, provided the only consistent exception to this pattern, though future work is needed to parse these effects from those of socioeconomic factors. CD severity during adolescence is a parsimonious index of liability for persistence of EP into adulthood that explains outcome variance above and beyond all other demographic and psychosocial predictors in this sample.

Indexed as

Criminal BehaviorExpressed EmotionJuvenile DelinquencyAdolescentAdolescent BehaviorAdultAge of OnsetAntisocial Personality DisorderConduct DisorderDangerous BehaviorDisease ProgressionFemaleHumansLongitudinal StudiesMalePrognosis

Identifiers

PMID30383806
PMCPMC6211688
OpenAlexW2898942007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.