ArticlePloS one2018
The macroeconomic burden of noncommunicable diseases in the United States: Estimates and projections.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Patient-Centered Digital Health Records and Their Effects on Health Outcomes: Systematic Review.Journal of medical Internet research · 2022Pooled it
- Pooled it
- The Economic Impact of Cirrhosis and Other Chronic Liver Diseases on Global, Regional, and National Economies.Clinical and translational gastroenterology · 2026Article
- Designing a Digital Twin for the Management of Noncommunicable Diseases: Protocol for a Pilot Study and Methodology Validation.JMIR research protocols · 2026Article
- The global macroeconomic burden of diabetes mellitus.Nature medicine · 2026Article
- Trends and Association of Environmental Exposure and Climate Change with Non-Communicable Diseases in Latin America.Healthcare (Basel, Switzerland) · 2025Article
- Review
- Estimation and prediction on the economic burden of schistosomiasis in 25 endemic countries.Infectious diseases of poverty · 2025Article
- Ageing Trajectories: Exposome-Driven Pathobiological Mechanisms and Implications for Prevention from Blue Zones and Italian Longevity Hotspots Such as Cilento and Sicilian Mountain Villages.International journal of molecular sciences · 2025Review
- Observational assessment of the utilization of donated point of care tests and glycemic control at free and charitable clinics across the United States.Practical laboratory medicine · 2025Article
- Home Environment as a Therapeutic Target for Prevention and Treatment of Chronic Diseases: Delivering Restorative Living Spaces, Patient Education and Self-Care by Bridging Biophilic Design, E-Commerce and Digital Health Technologies.International journal of environmental research and public health · 2025Article
- Article
- Digital-based physical activity interventions implemented across the League of Arab States: a scoping review.Oxford open digital health · 2025Review
- Food Chain and Food Policies: Causes and Solutions for the Obesity Pandemic.Methodist DeBakey cardiovascular journal · 2025Review
- Psychological distress in adolescence and later economic and health outcomes in the United States population: A retrospective and modeling study.PLoS medicine · 2025Article
- An investigation into the health status of the elderly population in China and the obstacles to achieving healthy aging.Scientific reports · 2024Article
- The potential of micro- and nanoplastics to exacerbate the health impacts and global burden of non-communicable diseases.Cell reports. Medicine · 2024Review
- Possibilities and limits of modelling of long-range economic consequences of air pollution - A case study.Heliyon · 2024Article
- The spatial relationship between long-term vacant housing and non-communicable diseases in U.S. shrinking and growing metropolitan areas.Cities (London, England) · 2024Article
- Retrospective review of medicine utilization for noncommunicable diseases in three public sector pharmacies in Jamaica.Revista panamericana de salud publica = Pan American journal of public health · 2024Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
We develop and calibrate a dynamic production function model to assess how noncommunicable diseases (NCDs) will affect U.S. productive capacity in 2015-2050. In this framework, aggregate output is produced according to a human capital-augmented production function that accounts for the effects of projected disease prevalence. NCDs influence the economy through the following pathways: 1) when working-age individuals die of a disease, aggregate output undergoes a direct loss because physical capital can only partially substitute for the loss of human capital in the production process. 2) If working-age individuals suffer from a disease but do not die from it, then, depending on the condition's severity, they tend to be less productive, might work less, or might retire earlier. 3) Current NCD interventions such as medical treatments and prevention require substantial resources. Part of these resources could otherwise be used for productive investments in infrastructure, education, or research and development. This implies a loss of savings across the population and hampers economy-wide physical capital accumulation. Our results indicate a total loss of USD94.9 trillion (in constant 2010 USD) due to all NCDs. Mental health conditions and cardiovascular diseases impose the highest burdens, followed by cancer, diabetes, and chronic respiratory diseases. In per capita terms, the economic burden of all NCDs in 2015-2050 is USD265,000. The total NCD burden roughly corresponds to an annual tax rate of 10.8% on aggregate income.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.