Evidence map›Paper›PMID 30383591›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2018

Genital HIV-1 Shedding With Dolutegravir (DTG) Plus Lamivudine (3TC) Dual Therapy.

Sara Gianella, Vincent C Marconi, Baiba Berzins, Constance A Benson, Paul Sax, Carl J Fichtenbaum, Timothy Wilkin, Millie Vargas, Qianqian Deng, Michelli F Oliveira and 2 more

Abstract readLetter
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sara GianellaDivision of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA.
Vincent C MarconiRollins School of Public Health, Emory University, School of Medicine, Atlanta, GA.
Baiba BerzinsDivision of Infectious Diseases, Northwestern University, Chicago, IL.
Constance A BensonDivision of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA.
Paul SaxDivision of Infectious Diseases, Brigham and Women's Hospital Boston, Boston, MA.
Carl J FichtenbaumUniversity of Cincinnati Medical Center, Cincinnati, OH.
Timothy WilkinDivision of Infectious Diseases, Weill Cornell Medicine, New York, NY.
Millie VargasDivision of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA.
Qianqian DengDivision of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA.
Michelli F OliveiraDivision of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA.
Carlee MoserDepartment of Biostatistics, Center for Biostatistics and AIDS Research, Harvard TH Chan School of Public Health, Boston, MA.
Babafemi O TaiwoDivision of Infectious Diseases, Northwestern University, Chicago, IL.

Funding

Leadership and Operations Center (LOC), AIDS Clinical Trials Group (ACTG); LOC 1/UM1AI068636 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, RAJESH T GANDHI · 2011 to 2026
$1073.1M
Statistical and Data Management Center (SDMC), AIDS Clinical Trials Group (ACTG)UM1AI068634 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Marlene Ann Cooper, Michael David Hughes · 2011 to 2026
$246.6M
AIDS Clinical Trials Group NetworkU01AI068636 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI KURITZKES, DANIEL R. · 2006 to 2010
$147.1M
Validation, CLIA and Qualification (VQC): Enhancing the RS ratio as a tool for AIDS Clinical Trial Group (ACTG) tuberculosis trialsUM1AI106701 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Grace M Aldrovandi · 2014 to 2026
$116.8M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Maile Ann Young Karris · 1994 to 2026
$78.4M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
Statistical and Data Management Center for the AIDS Clinical Trials GroupU01AI068634 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI HUGHES, MICHAEL DAVID · 2006 to 2010
$71.9M
Harvard Medical School Vaccine Clinical Trials UnitUM1AI069412 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Lindsey Robert Baden, Daniel R. Kuritzkes · 2012 to 2026
$57.2M
UCSD Department of Medicine HIV/AIDS Clinical Trials UnitUM1AI069432 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TIMOTHY J. WILKIN · 2012 to 2026
$50.4M
STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jennifer E Iudicello · 2001 to 2026
$50.4M
Virology and Immunology Technology CoreP30AI117943 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Mohamed Abdel Mohsen · 2015 to 2026
$38.4M
Northwestern University Clinical Trial UnitUM1AI069471 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Chad J Achenbach · 2012 to 2026
$24.6M
NIAID NIH HHS P30 AI036214NIAID NIH HHS P30 AI050409NIAID NIH HHS P30 AI117943NIAID NIH HHS R21 AI134295NIAID NIH HHS U01 AI068634NIAID NIH HHS U01 AI068636NIAID NIH HHS UM1 AI068634NIAID NIH HHS UM1 AI068636NIAID NIH HHS UM1 AI069412NIAID NIH HHS UM1 AI069432NIAID NIH HHS UM1 AI069471NIAID NIH HHS UM1 AI106701NICHD NIH HHS P01 HD040540NICHD NIH HHS R21 HD094646NIMH NIH HHS P30 MH062512
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Virus SheddingAnti-HIV AgentsDolutegravirFemaleGenitaliaGenotyping TechniquesHeterocyclic Compounds, 3-RingHIV-1HIV InfectionsHumansLamivudineMaleOxazinesPiperazinesPyridonesRNA, ViralAnti-HIV AgentsDolutegravirHeterocyclic Compounds, 3-RingLamivudineOxazinesPiperazinesPyridonesRNA, Viral

Identifiers

PMID30383591
PMCPMC6231952

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.