Evidence map›Paper›PMID 30383590›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2019

Opioid Misuse Among HIV-Positive Adults in Medical Care: Results From the Medical Monitoring Project, 2009-2014.

Ansley Lemons, Nicholas DeGroote, Alejandro Peréz, Jason Craw, Margaret Nyaku, Dita Broz, Christine L Mattson, Linda Beer

Open access · greenAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 35 citations in OpenAlex.

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  17. Opioid and neuroHIV Comorbidity - Current and Future Perspectives.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ansley LemonsDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
Nicholas DeGrooteDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
Alejandro PerézDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
Jason CrawDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
Margaret NyakuDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
Dita BrozDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
Christine L MattsonDivision of Unintentional Injury Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
Linda BeerDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
Centers for Disease Control and Prevention · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundPeople living with HIV are prescribed opioids more often and at higher doses than people who do not have HIV, and disproportionately experience risk factors for substance use disorder, which suggests they could be at increased risk of the misuse of opioids. Researchers also suggest that opioid misuse negatively affects various HIV clinical outcomes, increasing the risk of transmission to partners with an HIV-negative status.

methodsWe calculated weighted percentages and 95% confidence intervals to estimate substance use characteristics among a probability sample of 28,162 HIV-positive adults receiving medical care in the United States who misused opioids (n = 975). Then, we used Rao-Scott χ tests to assess bivariate associations between opioid misuse and selected characteristics.

resultsIn all, 3.3% misused opioids. Misuse was more common among young adults, males, and non-Hispanic whites. Persons who misused opioids were less likely to: have been prescribed antiretroviral therapy (ART) (88.7%), report being adherent to ART medications in the past 3 days (78.1%), and have durable viral suppression (54.3%) than persons who did not misuse opioids (92.5%, 87.7%, and 64.7%, respectively). Persons who misused opioids were more likely to report condomless sex with partners of negative or unknown HIV status while not durably virally suppressed (11.7% vs 3.4%) than persons who did not misuse opioids.

conclusionsOpioid misuse among adults receiving HIV medical care is associated with inadequate ART adherence, insufficient durable viral suppression, and higher risk of HIV transmission to sexual partners.

Indexed as

AdultAnalgesics, OpioidDrug MonitoringFemaleHIV InfectionsHumansMaleMiddle AgedOpioid-Related DisordersPrescription Drug MisuseProgram EvaluationUnited StatesUnsafe SexViral LoadYoung AdultAnalgesics, Opioid

Identifiers

PMID30383590
PMCPMC6357776
OpenAlexW2899488461

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.