Evidence map›Paper›PMID 30383415›Full record

ArticleAmerican journal of public health2018

Potential Impact of HIV Preexposure Prophylaxis Among Black and White Adolescent Sexual Minority Males.

Deven T Hamilton, Steven M Goodreau, Samuel M Jenness, Patrick S Sullivan, Li Yan Wang, Richard L Dunville, Lisa C Barrios, Eli S Rosenberg

Abstract read
In one paragraph

Article in American journal of public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Experiences of Successful PrEP Uptake Among Adolescent Sexual Minority Men in the United States: A Qualitative Exploration.AIDS education and prevention : official publication of the International Society for AIDS Education · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Preexposure Prophylaxis for Prevention of HIV Acquisition Among Adolescents: Clinical Considerations, 2020.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Deven T HamiltonDeven T. Hamilton is with the Center for Studies in Demography and Ecology and Steven M. Goodreau is with the Department of Anthropology, University of Washington, Seattle. Samuel M. Jenness and Patrick S. Sullivan are with the Department of Epidemiology, Emory University, Atlanta, GA. Li Yan Wang, Richard L. Dunville, and Lisa C. Barrios are with the Division of Adolescent and School Health, Centers for Disease Control and Prevention, Atlanta, GA. Eli S. Rosenberg is with the Department of Epidemiology and Biostatistics, University at Albany School of Public Health, State University of New York, Rensselaer.
Steven M GoodreauDeven T. Hamilton is with the Center for Studies in Demography and Ecology and Steven M. Goodreau is with the Department of Anthropology, University of Washington, Seattle. Samuel M. Jenness and Patrick S. Sullivan are with the Department of Epidemiology, Emory University, Atlanta, GA. Li Yan Wang, Richard L. Dunville, and Lisa C. Barrios are with the Division of Adolescent and School Health, Centers for Disease Control and Prevention, Atlanta, GA. Eli S. Rosenberg is with the Department of Epidemiology and Biostatistics, University at Albany School of Public Health, State University of New York, Rensselaer.
Samuel M JennessDeven T. Hamilton is with the Center for Studies in Demography and Ecology and Steven M. Goodreau is with the Department of Anthropology, University of Washington, Seattle. Samuel M. Jenness and Patrick S. Sullivan are with the Department of Epidemiology, Emory University, Atlanta, GA. Li Yan Wang, Richard L. Dunville, and Lisa C. Barrios are with the Division of Adolescent and School Health, Centers for Disease Control and Prevention, Atlanta, GA. Eli S. Rosenberg is with the Department of Epidemiology and Biostatistics, University at Albany School of Public Health, State University of New York, Rensselaer.
Patrick S SullivanDeven T. Hamilton is with the Center for Studies in Demography and Ecology and Steven M. Goodreau is with the Department of Anthropology, University of Washington, Seattle. Samuel M. Jenness and Patrick S. Sullivan are with the Department of Epidemiology, Emory University, Atlanta, GA. Li Yan Wang, Richard L. Dunville, and Lisa C. Barrios are with the Division of Adolescent and School Health, Centers for Disease Control and Prevention, Atlanta, GA. Eli S. Rosenberg is with the Department of Epidemiology and Biostatistics, University at Albany School of Public Health, State University of New York, Rensselaer.
Li Yan WangDeven T. Hamilton is with the Center for Studies in Demography and Ecology and Steven M. Goodreau is with the Department of Anthropology, University of Washington, Seattle. Samuel M. Jenness and Patrick S. Sullivan are with the Department of Epidemiology, Emory University, Atlanta, GA. Li Yan Wang, Richard L. Dunville, and Lisa C. Barrios are with the Division of Adolescent and School Health, Centers for Disease Control and Prevention, Atlanta, GA. Eli S. Rosenberg is with the Department of Epidemiology and Biostatistics, University at Albany School of Public Health, State University of New York, Rensselaer.
Richard L DunvilleDeven T. Hamilton is with the Center for Studies in Demography and Ecology and Steven M. Goodreau is with the Department of Anthropology, University of Washington, Seattle. Samuel M. Jenness and Patrick S. Sullivan are with the Department of Epidemiology, Emory University, Atlanta, GA. Li Yan Wang, Richard L. Dunville, and Lisa C. Barrios are with the Division of Adolescent and School Health, Centers for Disease Control and Prevention, Atlanta, GA. Eli S. Rosenberg is with the Department of Epidemiology and Biostatistics, University at Albany School of Public Health, State University of New York, Rensselaer.
Lisa C BarriosDeven T. Hamilton is with the Center for Studies in Demography and Ecology and Steven M. Goodreau is with the Department of Anthropology, University of Washington, Seattle. Samuel M. Jenness and Patrick S. Sullivan are with the Department of Epidemiology, Emory University, Atlanta, GA. Li Yan Wang, Richard L. Dunville, and Lisa C. Barrios are with the Division of Adolescent and School Health, Centers for Disease Control and Prevention, Atlanta, GA. Eli S. Rosenberg is with the Department of Epidemiology and Biostatistics, University at Albany School of Public Health, State University of New York, Rensselaer.
Eli S RosenbergDeven T. Hamilton is with the Center for Studies in Demography and Ecology and Steven M. Goodreau is with the Department of Anthropology, University of Washington, Seattle. Samuel M. Jenness and Patrick S. Sullivan are with the Department of Epidemiology, Emory University, Atlanta, GA. Li Yan Wang, Richard L. Dunville, and Lisa C. Barrios are with the Division of Adolescent and School Health, Centers for Disease Control and Prevention, Atlanta, GA. Eli S. Rosenberg is with the Department of Epidemiology and Biostatistics, University at Albany School of Public Health, State University of New York, Rensselaer.

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
Methods and Data CoreR24HD042828 · NICHD · UNIVERSITY OF WASHINGTON · PI MAR, CORINNE M · 2002 to 2016
$9.3M
Scientific/Technical CoreP2CHD042828 · NICHD · UNIVERSITY OF WASHINGTON · PI SARA R. CURRAN · 2017 to 2026
$6.3M
Statistical Methods for Network EpidemiologyR01HD068395 · NICHD · UNIVERSITY OF WASHINGTON · PI MORRIS, WANDA MARTINA · 2011 to 2015
$3.0M
EpiModel 2.0: Integrated Network Models for HIV/STI Prevention ScienceR01AI138783 · NIAID · EMORY UNIVERSITY · PI JENNESS, SAMUEL · 2018 to 2021
$3.0M
ENHANCING MODELS OF HIV, VIRAL HEPATITIS, STIs, AND TUBERCULOSIS TO INFORM AND IMPROVE PUBLIC HEALTH IMPACTU38PS004646 · PS · EMORY UNIVERSITY · PI SULLIVAN, PATRICK · 2014 to 2015
$2.9M
Modeling Antiretroviral-Based Prevention among MSM in the USR21MH112449 · NIMH · EMORY UNIVERSITY · PI JENNESS, SAMUEL · 2017 to 2018
$442k
Using Sexual Network Transmission Models to Explain HIV Disparities Between BlackR21HD075662 · NICHD · UNIVERSITY OF WASHINGTON · PI GOODREAU, STEVEN M. · 2013 to 2014
$418k
NCHHSTP CDC HHS U38 PS004646NIAID NIH HHS P30 AI027757NIAID NIH HHS P30 AI050409NIAID NIH HHS R01 AI138783NICHD NIH HHS P2C HD042828NICHD NIH HHS R01 HD068395NICHD NIH HHS R21 HD075662NICHD NIH HHS R24 HD042828NIMH NIH HHS R21 MH112449
6 · The paper itself

Abstract

objectivesTo assess the potential impact of preexposure prophylaxis (PrEP) on the HIV epidemic among Black and White adolescent sexual minority males (ASMM).

methodsWe used a network model and race-specific data from recent trials to simulate HIV transmission among a population of Black and White 13- to 18-year-old ASMM over 20 years. We estimated the number of infections prevented (impact) and the number needed to treat to prevent an infection (efficiency) under multiple coverage and adherence scenarios.

resultsAt modeled coverage and adherence, PrEP could avert 3% to 20% of infections among Black ASMM and 8% to 51% among White ASMM. A larger number, but smaller percentage, of infections were prevented in Black ASMM in all scenarios examined. PrEP was more efficient among Black ASMM (number needed to treat to avert an infection = 25-32) compared with White ASMM (146-237).

conclusionsPrEP can reduce HIV incidence among both Black and White ASMM but is far more efficient for Black ASMM because of higher incidence. Public Health Implications. Black ASMM communities suffer disproportionate HIV burden; despite imperfect adherence, PrEP programs could prevent HIV efficiently in these communities.

Indexed as

HIV InfectionsAdolescentBlack or African AmericanHomosexuality, MaleHumansMalePre-Exposure ProphylaxisRetrospective StudiesSexual and Gender MinoritiesWhite People

Identifiers

PMID30383415
PMCPMC6215365

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.