ReviewCurrent opinion in neurology2018
Active recovery from concussion.
Review in Current opinion in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 66 citations in OpenAlex.
- Optimal Volume of Moderate-to-Vigorous Physical Activity Postconcussion in Children and Adolescents.JAMA network open · 2024Trial
- Transcranial low-frequency pulsating electromagnetic fields (T-PEMF) as post-concussion syndrome treatment.Acta neurologica Scandinavica · 2020Trial
- Rehabilitation Involving Tailored Subsymptomatic Aerobic Exercise in Adult Patients With Persistent Postconcussion Symptoms (REPCon Project): Protocol for an Assessor-Blinded, Parallel-Group, Randomized Controlled Trial.JMIR research protocols · 2026Article
- Symptom Resolution Characteristics: Initial Symptom Trajectories of Collegiate Students with and without Persisting Symptoms After Concussion.Sports medicine (Auckland, N.Z.) · 2026Article
- A One-Year Retrospective Study of the Occurrence of Sport-Related Concussions in Japanese University Sports: Characteristics of Athletes with Multiple Occurrences.Sports (Basel, Switzerland) · 2026Article
- An International Physical Exercise Screening Questionnaire (IPESQ).International journal of emergency medicine · 2026Review
- Concussion and the Autonomic, Immune, and Endocrine Systems: An Introduction to the Field and a Treatment Framework for Persisting Symptoms.Journal of personalized medicine · 2025Review
- Diagnosis and Management of Mild Traumatic Brain Injury (mTBI): A Comprehensive, Patient-centered Approach.Current pain and headache reports · 2025Review
- Use of the Buffalo Concussion Treadmill Test in community adult patients with mild traumatic brain injury.PM & R : the journal of injury, function, and rehabilitation · 2024Observational
- Exercise and Recovery Following Mild-to-Moderate Traumatic Brain Injury in the Community Setting.Cureus · 2024Article
- TBICoE approach to concussion rehabilitation in service members and veterans.NeuroRehabilitation · 2024Review
- Headpulse Biometric Measures Following Concussion in Young Adult Athletes.JAMA network open · 2023Article
- The Effectiveness of Physical Therapy Interventions for Athletes Post-Concussion: A Systematic Review.International journal of sports physical therapy · 2023Article
- Sports-related concussion: assessing the comprehension, collaboration, and contribution of chiropractors.Chiropractic & manual therapies · 2022Article
- The role of the stress system in recovery after traumatic brain injury: A tribute to Bruce S. McEwen.Neurobiology of stress · 2022Article
- Concussions: understanding the invisible injury.Canadian family physician Medecin de famille canadien · 2022Article
- Clinical Assessment of Concussion and Persistent Post-Concussive Symptoms for Neurologists.Current neurology and neuroscience reports · 2021Review
- More Physical Activity after Concussion Is Associated with Faster Return to Play among Adolescents.International journal of environmental research and public health · 2021Article
- Post-COVID-19 Syndrome (Long Haul Syndrome): Description of a Multidisciplinary Clinic at Mayo Clinic and Characteristics of the Initial Patient Cohort.Mayo Clinic proceedings · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewRecent studies are challenging the utility of prolonged rest as treatment for concussion and postconcussion syndrome (PCS). The purpose of this paper is to review the evidence for active recovery from concussion and PCS. RECENT
findingsEmerging data identify the central role of autonomic nervous system (ANS) dysfunction in concussion pathophysiology. The exercise intolerance demonstrated by athletes after sport-related concussion may be related to abnormal ANS regulation of cerebral blood flow. As aerobic exercise training improves ANS function, sub-symptom threshold exercise treatment is potentially therapeutic for concussion. A systematic assessment of exercise tolerance using the Buffalo Concussion Treadmill Test has been safely employed to prescribe a progressive, individualized subthreshold aerobic exercise treatment program that can return patients to sport and work. Multiple studies are demonstrating the efficacy of an active approach to concussion management. SUMMARY: Sustained rest from all activities after concussion, so-called 'cocoon therapy', is not beneficial to recovery. Evidence supports the safety, tolerability, and efficacy of controlled sub-symptom threshold aerobic exercise treatment for PCS patients. Further study should determine the efficacy and optimal timing, dose, and duration of subthreshold aerobic exercise treatment acutely after concussion because early intervention has potential to prevent PCS.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.