Evidence map›Paper›PMID 30382899›Full record

ArticleJournal of medical case reports2018

Multidrug-resistant Aeromonas hydrophila causing fatal bilateral necrotizing fasciitis in an immunocompromised patient: a case report.

Alejandra Ugarte-Torres, Sarah Perry, Angela Franko, Deirdre L Church

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

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  11. Frontiers in microbiology · 2022
    Review
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  15. Prevalence of Potentially Pathogenic Antibiotic-ResistantApplied and environmental microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alejandra Ugarte-TorresDepartment of Medicine, University of Calgary, 9-3535 Research Rd NW, Calgary, AB, T2L 2K8, Canada.
Sarah PerryDepartment of Medicine, University of Calgary, 9-3535 Research Rd NW, Calgary, AB, T2L 2K8, Canada.
Angela FrankoDepartment of Pathology and Laboratory Medicine, University of Calgary, Calgary, Canada.
Deirdre L ChurchDepartment of Medicine, University of Calgary, 9-3535 Research Rd NW, Calgary, AB, T2L 2K8, Canada. deirdre.church@cls.ab.ca.
University of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAeromonas hydrophila is a water-dwelling, gram-negative rod-shaped bacterium, associated with diarrheal illness and, less commonly, necrotizing skin and soft tissue infections, especially among immunocompromised patients. Necrotizing fasciitis is associated with a high mortality rate, especially when caused by Aeromonas spp. Our patient was infected with an extremely aggressive form of multidrug-resistant Aeromonas spp. that produced both an extended-spectrum β-lactamase and an AmpC enzyme. Aeromonads are being recognized as important emerging pathogens because of their inherent antibiotic resistance profiles compounded by other virulence factors. These difficult-to-treat organisms can have significant implications in both clinical and public health settings. CASE PRESENTATION: A 37-year-old Caucasian male with immunosuppression due to aplastic anemia being treated with cyclosporine, presented to hospital with relapsed disease. While in hospital, he subsequently developed overwhelming sepsis secondary to bilateral lower extremity necrotizing fasciitis. The necrotizing fasciitis was caused by a multidrug-resistant strain of A. hydrophila. Despite broad-spectrum antibiotics and aggressive surgical debridement, he succumbed to this severe invasive infection.

conclusionsNecrotizing fasciitis caused by Aeromonas spp. is a rare infection that may have a poor clinical outcome, particularly if the diagnosis is delayed and/or the organism is highly virulent and multidrug resistant. Enhanced education of clinicians and microbiologists is required to prevent unnecessary complications and improve survival.

Indexed as

AdultAeromonas hydrophilaAnemia, AplasticCyclosporineDrug Resistance, Multiple, BacterialFasciitis, NecrotizingFatal OutcomeGram-Negative Bacterial InfectionsHumansImmunocompromised HostMaleSepsisSoft Tissue InfectionsCyclosporineAeromonas hydrophilaMultidrug resistanceNecrotizing fasciitis

Identifiers

PMID30382899
PMCPMC6211551
OpenAlexW2898581951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.