ArticleCardiovascular ultrasound2018
Left atrial strain - an early marker of left ventricular diastolic dysfunction in patients with hypertension and paroxysmal atrial fibrillation.
Article in Cardiovascular ultrasound, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06417112 (Can Left Atrial Strain Measurements, and Correlating Changes in Left Atrium Area and Volume Size, be Used as an Early Predictor of Atrial Fibrillation?), which is not on this map. Cited by 47 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Can Left Atrial Strain Measurements, and Correlating Changes in Left Atrium Area and Volume Size, be Used as an Early Predictor of Atrial Fibrillation?
Who cites it
47 citing papers in PubMed.
- Peak atrial longitudinal strain is predictive of atrial fibrillation in patients with chronic obstructive pulmonary disease and coronary artery disease.Echocardiography (Mount Kisco, N.Y.) · 2021Trial
- Left and Right Atrial Strain Across the Heart Failure Continuum: Multifaceted Markers of Subclinical Mechanical Dysfunction and Haemodynamic Burden.Diagnostics (Basel, Switzerland) · 2026Review
- Mitral Annular Calcification and Its Severity in Relation to Left Atrial Reservoir Strain and a Non-Invasive Left Atrial Stiffness Index.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Quantitative evaluation of left atrial function via two-dimensional speckle-tracking echocardiography in patients with different grades of hypertension.Quantitative imaging in medicine and surgery · 2026Article
- Early Divergent Cardiac Adaptation After Hematopoietic Stem Cell Transplantation: A Multimodal Echocardiographic and Electrocardiographic Study.Diagnostics (Basel, Switzerland) · 2026Article
- How Does Right Atrial Function Differ? A Speckle-Tracking Echocardiographic Comparison of Fetuses With Left Ventricular Outflow Tract Obstruction Versus Those With Significant Tricuspid Regurgitation.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Echocardiographic strain imaging and progression of atrial fibrillation in low-risk individuals.International journal of cardiology. Heart & vasculature · 2026Article
- Risk stratifying systemic sclerosis-related pulmonary hypertension by left atrial strain.Rheumatology (Oxford, England) · 2026Article
- CMR-based left atrial strain for predicting left ventricular diastolic dysfunction in asymptomatic hypertensive patients.Quantitative imaging in medicine and surgery · 2025Article
- Three-dimensional left atrial strain is associated with heart failure and cardiovascular death in the general population.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Diagnostic implication of left atrial stiffness index in patients with SLE with left ventricular diastolic dysfunction.Lupus science & medicine · 2025Article
- Vendor and software based variation in left atrial strain measurements: implications for clinical practice.The international journal of cardiovascular imaging · 2025Article
- Early cardiovascular changes in hypertensive pregnancies: insights from left atrial strain and compliance.BMC pregnancy and childbirth · 2025Observational
- Diagnostic and prognostic potential of left atrial strain in cardiovascular disease: a narrative review.Journal of echocardiography · 2025Review
- Evaluation of left atrial strain changes in patients with breast cancer after anthracycline therapy.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025Article
- Application of cardiac magnetic resonance feature tracking (CMR-FT) for quantitative assessment of left atrial function in nonobstructive hypertrophic cardiomyopathy.Quantitative imaging in medicine and surgery · 2025Article
- Investigating Left Atrial Diameter and Heart Failure Onset in Middle-Aged and Elderly: A Retrospective-Prospective Study.Clinical cardiology · 2025Article
- Study on the ultrasonic myocardial mechanics of left atrioventricular coupling in IBSH patients.Frontiers in cardiovascular medicine · 2025Article
- Comparing Left Atrial Strain and the HFA-PEFF Score in Diagnosing Heart Failure with Preserved Ejection Fraction: A Cross-Sectional Study.Research in heart yield and translational medicine · 2025Article
- LA PULSE: Evaluating Left Atrial Function Pre- and Post-Atrial Fibrillation Ablation Using PULSEd Field Ablation.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background2D strain imaging of the left atrium (LA) is a new echocardiographic method which allows us to determine contractile, conduit and reservoir functions separately. This method is particularly useful when changes are subtle and not easily determined by traditional parameters, as it is in arterial hypertension and atrial fibrillation (AF). THE AIMS OF OUR STUDY WERE: to determine LA contractile, conduit and reservoir function by 2D strain imaging in patients with mild arterial hypertension and paroxysmal AF; to assess LA contractile, conduit and reservoir functions' relation with LV diastolic dysfunction (DD) parameters.
methodsLA contractile, conduit and reservoir functions together with echocardiographic signs of LV DD were assessed in 63 patients with arterial hypertension and paroxysmal AF. Patients were grouped according to number of signs showing LV DD (annular e' velocity: septal e' < 7 cm/s, lateral e' < 10 cm/s, average E/e' ratio > 14, LA volume index > 34 ml/m
resultsMean contractile, conduit and reservoir strains in all the patients were - 14.14 (± 5.83) %, 15.98 (± 4.85) % and 31.03 (± 7.64) % respectively. Contractile strain did not differ between the groups. Conduit strain was higher in patients with 0 signs compared with other groups (p = 0.016 vs 1 sign of LV DD and p = 0.001 vs 2 signs of LV DD). Reservoir strain was higher in patients with 0 signs compared with other groups (p = 0.014 vs 1 sign of LV DD and p < 0.001 vs 2 signs of LV DD).
conclusionsThe patients with paroxysmal AF and primary arterial hypertension have decreased reservoir, conduit and pump LA functions even in the absence of echocardiographic signs of LV DD. With increasing number of parameters showing LV DD, LA conduit and reservoir functions decrease while contractile does not change. LA conduit and reservoir functions decrease earlier than the diagnosis of LV DD can be established according to the guidelines in patients with primary arterial hypertension and AF.
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