Trial reportBMC oral health2018
A prospective clinical study to evaluate the performance of zirconium dioxide dental implants in single-tooth edentulous area: 3-year follow-up.
Trial report in BMC oral health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02163395 (A Prospective Open Label Single Arm Study to Evaluate the Performance of Straumann Monotype FullCeram), which is not on this map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Open Label Single Arm Study to Evaluate the Performance of Straumann Monotype FullCeram (Zirconium Dioxide) Implants in Single Tooth Gaps in the Maxilla and Mandible
Who cites it
26 citing papers in PubMed, 57 citations in OpenAlex.
- Metal-Free Custom-Made Zirconia Implants-A Prospective 5-Year Follow-Up Single-Arm Clinical Trial.Clinical implant dentistry and related research · 2025Trial
- In-vitro characterization and evaluation of innovative surface modifications of zirconia implants for the optimization of hard and soft tissue management.International journal of implant dentistry · 2026Article
- Fatigue Survival and Biomechanical Behavior of Two-piece Titanium and Zirconia Dental Implants.Journal of clinical and experimental dentistry · 2026Review
- Long-Term Clinical, Radiographic and Esthetic Outcomes of Zirconia Dental Implants: A 10-Year Prospective Multicenter Study.Clinical oral implants research · 2026Article
- A prospective observational study regarding host-derived immunological parameters around zirconia implants in comparison to natural teeth following flap surgery.Scientific reports · 2025Observational
- Patient-reported outcomes of esthetics, function and oral hygiene with single dental implants 10-15 years after placement: a cross-sectional study.Acta odontologica Scandinavica · 2025Article
- Primary Stability of Zirconia Dental Implants with Cylindrical and Tapered Designs Across Varying Bone Densities: An In Vitro Evaluation.Dentistry journal · 2024Article
- Evaluation of one-piece zirconia dental implants: An 8-year follow-up study.Clinical oral investigations · 2023Article
- In Vitro Investigation of Material Combinations for Meso- and Suprastructures in a Biomimetic Approach to Restore One-Piece Zirconia Implants.Materials (Basel, Switzerland) · 2023Article
- Influence of Surface Treatment and Accelerated Ageing on Biaxial Flexural Strength and Hardness of Zirconia.Materials (Basel, Switzerland) · 2023Article
- One-Piece Zirconia Oral Implants for the Support of Three-Unit Fixed Dental Prostheses: Three-Year Results from a Prospective Case Series.Journal of functional biomaterials · 2023Article
- Results at the 1-Year Follow-Up of a Prospective Cohort Study with Short, Zirconia Implants.Materials (Basel, Switzerland) · 2022Article
- Zirconia versus Titanium Implants: 8-Year Follow-Up in a Patient Cohort Contrasted with Histological Evidence from a Preclinical Animal Model.Materials (Basel, Switzerland) · 2022Article
- Effect of restoration material on marginal bone resorption around modified anatomic zirconia dental implants: A randomised controlled trial.Annals of medicine and surgery (2012) · 2022Article
- Surface Structure of Zirconia Implants: An Integrative Review Comparing Clinical Results with Preclinical and In Vitro Data.Materials (Basel, Switzerland) · 2022Review
- Influence of different zirconia surface treatments on biofilm formation in vitro and in situ.Clinical oral implants research · 2022Article
- A comparative evaluation of the metallic artifact generated by a ceramic dental implant and a titanium dental implant imaged on cone-beam computed tomographic scans: An ex vivo study.JADA foundational science · 2022Article
- In vivo and in vitro analysis in a rat model using zoledronate and alendronate medication: microbiological and scanning electron microscopy findings on peri-implant rat tissue.BMC oral health · 2021Article
- Comparative finite element analysis of mandibular posterior single zirconia and titanium implants: a 3-dimensional finite element analysis.The journal of advanced prosthodontics · 2021Article
- In Vitro Investigations in a Biomimetic Approach to Restore One-Piece Zirconia Implants.Materials (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTraditionally, dental implants have been made from titanium or titanium alloys. Alternatively, zirconia-based ceramic implants have been developed with similar characteristics of functional strength and osseointegration. Ceramic implants offer advantages in certain settings, e.g. in patients who object to metal dental implants. The aim of this study was to investigate the mid-term (36 months) clinical performance of a ceramic monotype implant in single-tooth edentulous area.
methodsThis was a prospective, open-label, single-arm study in patients requiring implant rehabilitation in single-tooth edentulous area. Ceramic implants (PURE Ceramic Implant, Institut Straumann AG, Basel, Switzerland) with a diameter of 4.1 mm were placed following standard procedure and loaded with provisional and final prostheses after 3 and 6 months, respectively. Implant survival rate and implant success rate were evaluated and crestal bone levels were measured by analysing standardized radiographs during implant surgery and at 6, 12, 24 and 36 months.
resultsForty-four patients received a study implant, of whom one patient withdrew consent after 3 months. With one implant lost during the first 6 months after surgery, the implant survival rate was 97.7% at 6 months. No further implants were lost over the following 30 months, and 3 patients were lost to follow-up during this time frame. This led to a survival rate of 97.5% at 36 months. Six months after implant surgery 93.0% of the implants were considered "successful", increasing to 97.6% at 12 months and remaining at this level at 24 months (95.1%) and 36 months (97.5%). Bone loss was most pronounced in the first half-year after implant surgery (0.88 ± 0.86 mm). By contrast, between 12 and 36 months the mean bone level remained stable (minimal gain of 0.06 [± 0.60] mm). Hence, the overall bone loss from implant surgery to 36 months was 0.97 (± 0.88) mm.
conclusionsIn the follow-up period ceramic implants can achieve favourable clinical outcomes on a par with titanium implants. For instance, these implants can be recommended for patients who object to metal dental implants. However, longer term studies with different edentulous morphology need to confirm the present data.
trial registrationRegistered on www.clinicaltrials.gov : NCT02163395 .
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