Evidence map›Paper›PMID 30382819›Full record

Trial reportBMC anesthesiology2018

Peep titration based on the open lung approach during one lung ventilation in thoracic surgery: a physiological study.

Michela Rauseo, Lucia Mirabella, Salvatore Grasso, Antonella Cotoia, Savino Spadaro, Davide D'Antini, Franca Valentino, Livio Tullo, Domenico Loizzi, Francesco Sollitto and 1 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03435523 (Optimal PEEP Based on the Open Lung Approach During One Lung Ventilation in Thoracic Surgery), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03435523 nacompletednot on this map

Optimal PEEP Based on the Open Lung Approach During One Lung Ventilation in Thoracic Surgery: a Physiological Study.

TypeinterventionalSponsorUniversity of FoggiaRan2012 to 2012Enrolled24ConditionsHypoxemiaArmsRecruitment maneuver
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Michela RauseoDepartment of Anesthesia and Intensive care, University of Foggia, Viale Pinto, 1-71100, Foggia, Italy. michela.rauseo@hotmail.it.ORCID 0000-0001-9718-7454
Lucia MirabellaDepartment of Anesthesia and Intensive care, University of Foggia, Viale Pinto, 1-71100, Foggia, Italy.
Salvatore GrassoDepartment of Anesthesia and Intensive care, University of Bari, Bari, Italy.
Antonella CotoiaDepartment of Anesthesia and Intensive care, University of Foggia, Viale Pinto, 1-71100, Foggia, Italy.
Savino SpadaroDepartment of Anesthesia and Intensive care, University of Ferrara, Ferrara, Italy.
Davide D'AntiniDepartment of Anesthesia and Intensive care, University of Foggia, Viale Pinto, 1-71100, Foggia, Italy.
Franca ValentinoDepartment of Anesthesia and Intensive care, University of Foggia, Viale Pinto, 1-71100, Foggia, Italy.
Livio TulloDepartment of Anesthesia and Intensive care, University of Foggia, Viale Pinto, 1-71100, Foggia, Italy.
Domenico LoizziDepartment of Thoracic Surgery, University of Foggia, Foggia, Italy.
Francesco SollittoDepartment of Thoracic Surgery, University of Foggia, Foggia, Italy.
Gilda CinnellaDepartment of Anesthesia and Intensive care, University of Foggia, Viale Pinto, 1-71100, Foggia, Italy.
University of Foggia · ITUniversity of Bari Aldo Moro · ITUniversity of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring thoracic surgery in lateral decubitus, one lung ventilation (OLV) may impair respiratory mechanics and gas exchange. We tested a strategy based on an open lung approach (OLA) consisting in lung recruitment immediately followed by a decremental positive-end expiratory pressure (PEEP) titration to the best respiratory system compliance (C

methodsIn thirteen patients undergoing upper left lobectomy we studied lung and chest wall mechanics, transpulmonary pressure (P

resultsThe external PEEP selected through the OLA was 6 ± 0.8 cmH

conclusionsIn our patients, the OLA strategy performed during OLV improved oxygenation and increased C

trial registrationTRN: ClinicalTrials.gov , NCT03435523 , retrospectively registered, Feb 14 2018.

Indexed as

AdultAgedAged, 80 and overFemaleHemodynamicsHumansLungMaleMiddle AgedOne-Lung VentilationPneumonectomyPositive-Pressure RespirationPulmonary Gas ExchangeRespiratory MechanicsThoracic Surgical ProceduresOne lung ventilationOpen lung approachRecruitment maneuverThoracic surgery

Identifiers

PMID30382819
PMCPMC6211445
OpenAlexW2899252776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.