Evidence map›Paper›PMID 30382815›Full record

ArticleBMC gastroenterology2018

Metabolic status and lifestyle factors associated with gallbladder polyps: a covariance structure analysis.

Song Leng, Ai Zhao, Qiang Li, Leilei Pei, Wei Zheng, Rui Liang, Hong Yan

Open access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Investigation of the relationship betweenFrontiers in microbiology · 2025
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  5. Exploring the interplay betweenFrontiers in microbiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Song LengDepartment of Epidemiology and Health Statistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Ai ZhaoSchool of Public Health, Peking University Health Science Center, Beijing, China.
Qiang LiDepartment of Epidemiology and Health Statistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Leilei PeiDepartment of Epidemiology and Health Statistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Wei ZhengDivision of Endocrinology and Metabolism, Department of obstetrics, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
Rui LiangHealth Management Center, The Second Hospital of Dalian Medical University, Dalian, China.
Hong YanDepartment of Epidemiology and Health Statistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China. xjtu_yh.paper@aliyun.com.
Xi'an Jiaotong University · CNBeijing Obstetrics and Gynecology Hospital · CNDalian Medical University · CNPeking University · CNSecond Affiliated Hospital of Dalian Medical University · CN

Funding

National Natural Science Foundation of Liaoning Province NO.:20170540239
6 · The paper itself

Abstract

backgroundGallbladder Polyps (GBP) are highly prevalent in China; however, the etiology of GBP has not been clearly defined. This study explored the associations between lifestyle factors and GBP and whether it mediated by metabolic factors or not.

methodsA total of 487 newly diagnosed GBP cases and 502 healthy controls were involved in this study. A questionnaire was used to investigate the socio-demographic characteristics and lifestyle factors. Food Intake Frequencies Questionnaire was used to obtain the food intake frequencies of seven food categories. Blood was tested for lipid profiles, fasting blood glucose and blood urine acid. A Covariance Structure Analysis was used in the analysis to explore the possible pathways between socio-demographic characteristics, lifestyle factors, metabolic factor and GBP.

resultsThe Covariance Structure Analysis showed that a higher BMI and elevated triglyceride level mediated the association between age and GBP. Lifestyle factors (smoking and drinking) and higher intake frequencies of fatty food (meat and viscera) also linked to higher BMI and higher triglyceride level, respectively, which were associated with GBP.

conclusionIn conclusion, age and lifestyle factors might be indirectly related with GBP through BMI and the triglyceride pathway.

Indexed as

Life StyleAdultAge FactorsAlcohol DrinkingBlood GlucoseBody Mass IndexDietExerciseFemaleGallbladder NeoplasmsHumansLipidsMaleMiddle AgedPolypsRisk FactorsBlood GlucoseLipidsUric AcidBlood lipidBody mass indexDietary intakeGallbladder polypsLifestyle factorsMetabolic status

Identifiers

PMID30382815
PMCPMC6211420
OpenAlexW2899003461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.