SynthesisInternational ophthalmology2019
The diagnostic value of optical coherence tomography angiography in diabetic retinopathy: a systematic review.
Synthesis in International ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 65 citations in OpenAlex.
- Prognostic value of expanded-field OCT angiography in visual acuity outcomes for non-proliferative diabetic retinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Topology-preserving, diameter-specific framework for conjunctival vessel segmentation and tortuosity analysis in diabetes.Scientific reports · 2026Article
- Graves ophthalmopathy a neglected comorbidity of graves' disease; a detailed investigation and management of sixty-eight patients in a tertiary healthcare center.BMC endocrine disorders · 2025Observational
- The association of islet autoantibodies with the neural retinal thickness and microcirculation in type 1 diabetes mellitus with no clinical evidence of diabetic retinopathy.Acta diabetologica · 2024Article
- Assessment of early macular microangiopathy in subjects with prediabetes using optical coherence tomography angiography and fundus photography.Acta diabetologica · 2024Article
- Optical coherence tomography angiography in diabetic retinopathy.Progress in retinal and eye research · 2023Review
- Microstructural Changes in the Macula Following Cataract Surgery in Patients with Type 2 Diabetes Mellitus Detected Using Optical Coherence Tomography Angiography.Diagnostics (Basel, Switzerland) · 2023Article
- Living Without a Diagnosis: A Patient's Perspective on Diabetic Macular Ischemia.Ophthalmology and therapy · 2022Article
- Article
- Response to 1-Year Fixed-Regimen Bevacizumab Therapy in Treatment-Naïve DME Patients: Assessment by OCT Angiography.Journal of diabetes research · 2022Article
- Update on Optical Coherence Tomography and Optical Coherence Tomography Angiography Imaging in Proliferative Diabetic Retinopathy.Diagnostics (Basel, Switzerland) · 2021Review
- Quantitative analysis of early diabetic retinopathy based on optical coherence tomography angiography biological image.World journal of clinical cases · 2021Article
- Quantitative analysis of retinal vessel density and thickness changes in diabetes mellitus evaluated using optical coherence tomography angiography: a cross-sectional study.BMC ophthalmology · 2021Observational
- Gastric Bypass Improves Microvascular Perfusion in Patients with Obesity.Obesity surgery · 2021Article
- Factors based on optical coherence tomography correlated with vision impairment in diabetic patients.Scientific reports · 2021Article
- Article
- Looking Ahead: Visual and Anatomical Endpoints in Future Trials of Diabetic Macular Ischemia.Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde · 2021Review
- Optical Coherence Tomography Angiography as a Noninvasive Assessment of Cerebral Microcirculatory Disorders Caused by Carotid Artery Stenosis.Disease markers · 2021Article
- A practical guide to optical coherence tomography angiography interpretation.International journal of retina and vitreous · 2020Review
- The vascular densities of the macula and optic disc in normal eyes from children by optical coherence tomography angiography.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDiabetic retinopathy (DR) is one of the leading causes of blindness worldwide. Accurate investigative tools are essential for the early diagnosis and monitoring of the disease. Optical coherence tomography angiography (OCTA) is a recently developed technology that enables visualisation of the retinal microvasculature.
methodsA systematic review of the literature was performed to examine the diagnostic use of OCTA in DR to date. Medline, EMBASE, and Cochrane databases were searched to find relevant studies. Sixty-one original studies were selected for the review. RESULTS AND DISCUSSION: OCTA has demonstrated the ability to identify microvascular features of DR such as microaneurysms, neovascularisation, and capillary non-perfusion. Furthermore, OCTA is enabling quantitative evaluation of the microvasculature of diabetic eyes. It has demonstrated the ability to detect early microvascular changes, in eyes with or without clinically evident DR. It has also been shown to detect progressive changes in the foveal avascular zone, and vascular perfusion density, with worsening severity of disease. It provides three-dimensional visualisation of the individual retinal vascular networks and is thereby enhancing our understanding of the role of the deeper vasculature in the pathogenesis of diabetic retinopathy and maculopathy.
conclusionHowever, limitations exist with current OCTA technology, in respect to the small field of view, image quality, projection artefact, and inaccuracies in analysis of the deeper vascular layers. While questions remain regarding its practical applicability in its present form, with continuing development and improvement of the technology, the diagnostic value of OCTA in diabetic retinopathy is likely to become evident.
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