ReviewPediatric nephrology (Berlin, Germany)2020
Cardiovascular risk factors in children on dialysis: an update.
Review in Pediatric nephrology (Berlin, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 31 citations in OpenAlex.
- Low dialysate sodium in children and young adults on maintenance hemodialysis: a prospective, randomized, crossover study.Pediatric nephrology (Berlin, Germany) · 2023Trial
- Association between immunologic risk factors and cardiovascular complications following pediatric kidney transplantation.Pediatric nephrology (Berlin, Germany) · 2026Article
- Non-infectious complications of peritoneal dialysis in children.Pediatric nephrology (Berlin, Germany) · 2025Review
- Development of Non-HLA Antibodies and Their Association With Antibody-Mediated Rejection in Pediatric Kidney Transplant Recipients.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- Evaluation of cardiac remodeling in pediatric chronic kidney disease by cardiovascular magnetic resonance.BMC cardiovascular disorders · 2024Article
- Prospective Study of Modifiable Risk Factors of Arterial Hypertension and Left Ventricular Hypertrophy in Pediatric Patients on Hemodialysis.Kidney international reports · 2024Article
- NT-proBNP as a Potential Marker of Cardiovascular Damage in Children with Chronic Kidney Disease.Journal of clinical medicine · 2021Article
- CKD-MBD post kidney transplantation.Pediatric nephrology (Berlin, Germany) · 2021Article
- Treatment of hyperphosphatemia: the dangers of aiming for normal PTH levels.Pediatric nephrology (Berlin, Germany) · 2020Article
- Vitamin D-regulated osteocytic sclerostin and BMP2 modulate uremic extraskeletal calcification.JCI insight · 2019Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular disease (CVD) is a life-limiting comorbidity in patients with chronic kidney disease (CKD). In childhood, imaging studies have demonstrated early phenotypic characteristics including increases in left ventricular mass, carotid artery intima-media thickness, and pulse wave velocity, which occur even in young children with early stages of CKD. Vascular calcifications are the signature of an advanced phenotype and are mainly found in adolescents and young adults treated with dialysis. Association studies have provided valuable information regarding the significance of a multitude of risk factors in promoting CVD in children with CKD by using intermediate endpoints of measurements of surrogate parameters of CVD. Dialysis aggravates pre-existing risk factors and accelerates the progression of CVD with additional dialysis-related risk factors. Coronary artery calcifications in children and young adults with CKD accumulate in a time-dependent manner on dialysis. Identification of risk factors has led to improved understanding of principal mechanisms of CKD-induced damage to the cardiovascular system. Treatment strategies include assessment and monitoring of individual risk factor load, optimization of treatment of modifiable risk factors, and intensified hemodialysis if early transplantation is not possible.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.