Evidence map›Paper›PMID 30382321›Full record

ArticlePediatric radiology2019

Contrast-enhanced MRI compared to direct joint visualization at arthroscopy in pediatric patients with suspected temporomandibular joint synovitis.

Jessica R Leschied, Ethan A Smith, Scott Baker, Shokoufeh Khalatbari, Sharon Aronovich

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Pediatric radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Jessica R LeschiedSection of Pediatric Radiology, C. S. Mott Children's Hospital, Department of Radiology, University of Michigan Health System, 1540 East Hospital Drive, Ann Arbor, MI, 48109-4252, USA. jleschi@med.umich.edu.ORCID http://orcid.org/0000-0003-3178-7291
Ethan A SmithSection of Pediatric Radiology, C. S. Mott Children's Hospital, Department of Radiology, University of Michigan Health System, 1540 East Hospital Drive, Ann Arbor, MI, 48109-4252, USA.
Scott BakerSection of Pediatric Radiology, C. S. Mott Children's Hospital, Department of Radiology, University of Michigan Health System, 1540 East Hospital Drive, Ann Arbor, MI, 48109-4252, USA.
Shokoufeh KhalatbariBiostatics, Michigan Institute for Clinical & Health Research, University of Michigan Health System, Ann Arbor, MI, USA.
Sharon AronovichDepartment of Oral and Maxillofacial Surgery, University of Michigan Health System, Ann Arbor, MI, USA.
Michigan Medicine · USCincinnati Children's Hospital Medical Center · USProMedica Toledo Hospital · USUniversity of Michigan · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1 TR002240
6 · The paper itself

Abstract

backgroundContrast-enhanced magnetic resonance imaging (MRI) has become the gold standard when assessing the temporomandibular joint (TMJ) in children. To our knowledge, no previous pediatric study has compared findings of TMJ MRI with direct visualization of the joint using arthroscopy.

objectiveTo determine if subjective findings on contrast-enhanced MRI of the temporomandibular joint correlate with arthroscopic findings of acute and chronic inflammation of the TMJ in children. MATERIALS AND

methodsPatients who had temporally related TMJ arthroscopy and contrast-enhanced TMJ MRI between March 2014 and March 2016 were identified. Imaging was retrospectively reviewed by two radiologists for erosions, condyle shape, bone marrow edema, effusion, severity of synovitis, joint space width measured in the coronal plane and enhancement ratio of the synovium relative to ipsilateral temporal lobe white matter. Joint space width was included because synovial thickening could widen the joint space. TMJ arthroscopy findings assessed included indicators of acute inflammation (active synovitis, number of joint sites affected, presence of retrodiscitis) and markers of chronic inflammation (hyperplastic synovitis, adhesions, disc perforation, chondromalacia). A Total Synovitis Score was given to all patients on arthroscopy, which multiplied the severity of active synovitis (0-4) with the number of joint recesses affected. Data were compared using the Fisher exact test and a P-value <0.05 was considered significant.

resultsThere was no significant correlation between subjective synovitis on MRI and active synovitis on arthroscopy; however, there was a significant correlation between joint space width and hyperplastic synovitis (P=0.04, 3.7 mm±0.8 vs. 2.9 mm±0.6) and a trend toward significance between subjective synovitis (P=0.08) and enhancement ratio of synovium (P=0.06) on MRI and hyperplastic synovitis on arthroscopy.

conclusionJoint space width and subjective synovitis on TMJ MRI correlate with arthroscopic findings of chronic synovitis. Increased joint space width may be useful when evaluating the TMJ with less time-intensive modalities, such as ultrasound. However, MRI findings did not correlate well with findings of acute inflammation on arthroscopy.

Indexed as

AdolescentArthroscopyChildContrast MediaFemaleHumansMagnetic Resonance ImagingMaleMeglumineOrganometallic CompoundsRetrospective StudiesSynovitisTemporomandibular Joint DisordersYoung AdultContrast Mediagadobenic acidMeglumineOrganometallic CompoundsArthroscopyChildrenJuvenile idiopathic arthritisMagnetic resonance imagingSynovitisTemporomandibular joint

Identifiers

PMID30382321
OpenAlexW2898929862

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.