Evidence map›Paper›PMID 30382319›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2019

Recommendations for the conduct of economic evaluations in osteoporosis: outcomes of an experts' consensus meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the US branch of the International Osteoporosis Foundation.

M Hiligsmann, J-Y Reginster, A N A Tosteson, S V Bukata, K G Saag, D T Gold, P Halbout, F Jiwa, E M Lewiecki, D Pinto and 13 more

Open access · hybridAbstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 9 pooled it
21.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 9 syntheses or guidelines pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Impact of Structural Differences on the Modeled Cost-Effectiveness of Noninvasive Prenatal Testing.Medical decision making : an international journal of the Society for Medical Decision Making · 2024
    Pooled it
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  6. Cost-effectiveness of anterior surgical decompression surgery for cervical degenerative disk disease: a systematic review of economic evaluations.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Pooled it
  7. Cost-effectiveness analyses of denosumab for osteoporosis: a systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
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  10. The cost-effectiveness of biosimilar denosumab in postmenopausal osteoporosis: implications of baseline fracture risk and drug price.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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  14. Incidence of first and subsequent fractures in multiple myeloma patients: a parallel cohort study using UK CPRD dataset.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  15. Clinical and economic impact of deep learning-enhanced opportunistic osteoporosis screening using chest radiographs with and without the osteoporosis self-assessment tool for Asians (OSTA).Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 20 institutions in 10 countries.

M HiligsmannDepartment of Health Services Research, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands. m.hiligsmann@maastrichtuniversity.nl.
J-Y ReginsterDepartment of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.
A N A TostesonThe Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
S V BukataUCLA Orthopaedic Center, Santa Monica, CA, USA.
K G SaagDivision of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
D T GoldDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
P HalboutInternational Osteoporosis Foundation, Nyon, Switzerland.
F JiwaPatients Societies at the International Osteoporosis Foundation, Osteoporosis Canada, Toronto, Canada.
E M LewieckiNew Mexico Clinical Research & Osteoporosis Center, Albuquerque, NM, USA.
D PintoDepartment of Physical Therapy, Marquette University, Milwaukee, USA.
J D AdachiDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
N Al-DaghriChair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.
O BruyèreDepartment of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.
M ChandranOsteoporosis and Bone Metabolism Unit, Department of Endocrinology, Singapore General Hospital, Singapore, Singapore.
C CooperMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
N C HarveyMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
T A EinhornNew York University Langone Health, New York, USA.
J A KanisCentre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK.
D L KendlerUniversity of British Columbia, Vancouver, Canada.
O D MessinaCosme Argerich Hospital and IRO medical research centre, Buenos Aires, Argentina.
R RizzoliService of Bone Diseases, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland.
L SiThe George Institute for Global Health, University of New South Wales, Kensington, NH, Australia.
S SilvermanCedars-Sinai Medical Center, UCLA School of Medicine and the OMC Clinical Research Center, Los Angeles, CA, USA.
King Saud University · SAArgerich Hospital · ARAustralian Catholic University · AUCedars-Sinai Medical Center · USDartmouth Institute for Health Policy and Clinical Practice · USDuke University Hospital · USMaastricht University · NLMacquarie University · AUMcMaster University · CAMRC Lifecourse Epidemiology Unit · GBNew Mexico Clinical Research & Osteoporosis Center · USNorthwestern University · USNYU Langone Health · USOrthopaedic Center · USOsteoporosis Canada · CASingapore General Hospital · SGUniversity Hospital of Geneva · CHUniversity of Alabama at Birmingham · USUniversity of British Columbia · CAUniversity of Liège · BE

Funding

Department of Health 10/33/04Department of Health HTA/10/33/04Medical Research Council G0400491Medical Research Council G0601019Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1014Medical Research Council MC_UP_A620_1015Medical Research Council MC_UU_12011/1Medical Research Council MC_UU_12011/2Versus Arthritis 17702Versus Arthritis 21231
6 · The paper itself

Abstract

Economic evaluations are increasingly used to assess the value of health interventions, but variable quality and heterogeneity limit the use of these evaluations by decision-makers. These recommendations provide guidance for the design, conduct, and reporting of economic evaluations in osteoporosis to improve their transparency, comparability, and methodologic standards.

introductionThis paper aims to provide recommendations for the conduct of economic evaluations in osteoporosis in order to improve their transparency, comparability, and methodologic standards.

methodsA working group was convened by the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis to make recommendations for the design, conduct, and reporting of economic evaluations in osteoporosis, to define an osteoporosis-specific reference case to serve a minimum standard for all economic analyses in osteoporosis, to discuss methodologic challenges and initiate a call for research. A literature review, a face-to-face meeting in New York City (including 11 experts), and a review/approval by a larger group of experts worldwide (including 23 experts in total) were conducted.

resultsRecommendations on the type of economic evaluation, methods for economic evaluation, modeling aspects, base-case analysis and population, excess mortality, fracture costs and disutility, treatment characteristics, and model validation were provided. Recommendations for reporting economic evaluations in osteoporosis were also made and an osteoporosis-specific checklist was designed that includes items to report when performing an economic evaluation in osteoporosis. Further, 12 minimum criteria for economic evaluations in osteoporosis were identified and 12 methodologic challenges and need for further research were discussed.

conclusionWhile the working group acknowledges challenges and the need for further research, these recommendations are intended to supplement general and national guidelines for economic evaluations, improve transparency, quality, and comparability of economic evaluations in osteoporosis, and maintain methodologic standards to increase their use by decision-makers.

Indexed as

Cost-Benefit AnalysisHealth Care CostsHumansModels, EconometricOsteoporosisOsteoporotic FracturesQuality-Adjusted Life YearsResearch DesignCost-effectivenessEconomic evaluationOsteoporosisRecommendationsReference case

Identifiers

PMID30382319
PMCPMC6331734
OpenAlexW2899004149

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.