Evidence map›Paper›PMID 30382301›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2019

Prognostic analysis of interim

Ling Yuan, Michael C Kreissl, Liping Su, Zhifang Wu, Marcus Hacker, Jianzhong Liu, Xi Zhang, Yunfeng Bo, Hongyu Zhang, Xiang Li and 1 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Article
  3. Evaluating ΔMTV%, ΔDDiscover oncology · 2025
    Article
  4. Article
  5. Article
  6. Analysis of Positive Results ofDiagnostics (Basel, Switzerland) · 2023
    Article
  7. Aberrant patterns of PET response during treatment for DLBCL patients with MYC gene rearrangements.European journal of nuclear medicine and molecular imaging · 2022
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Ling YuanDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, No. 85, Jiefang Road, Taiyuan, 030001, Shanxi, China.
Michael C KreisslDepartment of Radiology and Nuclear Medicine, University Hospital Magdeburg, Magdeburg, Germany.
Liping SuDepartment of Hematology, Tumor Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Zhifang WuDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, No. 85, Jiefang Road, Taiyuan, 030001, Shanxi, China.
Marcus HackerDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, No. 85, Jiefang Road, Taiyuan, 030001, Shanxi, China.
Jianzhong LiuDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, No. 85, Jiefang Road, Taiyuan, 030001, Shanxi, China.
Xi ZhangDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, No. 85, Jiefang Road, Taiyuan, 030001, Shanxi, China.
Yunfeng BoDepartment of Pathology, Tumor Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Hongyu ZhangDepartment of PET/CT, Tumor Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Xiang LiDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Währinger Gürthel 18-20, Floor 3L, 1090, Vienna, Austria. xiang.li@meduniwien.ac.at.ORCID 0000-0002-0016-6233
Sijin LiDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, No. 85, Jiefang Road, Taiyuan, 030001, Shanxi, China. lisjnm123@163.com.
Shanxi Medical University · CNMedical University of Vienna · ATUniversity Hospital Magdeburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectives

methodsSixty primary DLBCL patients (31 females) were analyzed. Baseline and follow-up

resultsThe optimal cutoff for the prediction of treatment outcome was a ΔSUVmax% of 57% (after one cycle) and 63% (after two cycles); we could not detect a difference in accuracy with respect to a PET scan performed after one cycle and two cycles of chemotherapy (P  > 0.05). The ΔSUVmax% and the D-5PS (score 5) showed the highest prognostic value compared to a score of 3 and/or 4 (both after one cycle and two cycles). No significant difference in sensitivity, specificity, accuracy, or the area of under the curve (AUC) of ΔSUVmax% and D-5PS (score 5) was observed between PETs performed after one cycle or two cycles of therapy (P  > 0.05). ΔSUVmax%, D-5PS (score 5), and MYC gene rearrangement correlated significantly (P  < 0.001).

conclusionInterim

Indexed as

Fluorodeoxyglucose F18Positron Emission Tomography Computed TomographyAdultAgedAged, 80 and overFemaleGene Expression Regulation, NeoplasticGene RearrangementGenes, mycHumansKaplan-Meier EstimateLymphoma, Large B-Cell, DiffuseMaleMiddle AgedPrognosisRetrospective StudiesFluorodeoxyglucose F18Deauville five-point scaleDiffuse large B cell lymphomaInterim 18F-FDG PET/CTMYC geneSUVmax

Identifiers

PMID30382301
PMCPMC6333726
OpenAlexW2899342868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.