Evidence map›Paper›PMID 30382146›Full record

ArticleScientific reports2018

N-glycan Remodeling Using Mannosidase Inhibitors to Increase High-mannose Glycans on Acid α-Glucosidase in Transgenic Rice Cell Cultures.

Hong-Yeol Choi, Heajin Park, Jong Kwang Hong, Sun-Dal Kim, Jun-Young Kwon, SeungKwan You, Jonghye Do, Dong-Yup Lee, Ha Hyung Kim, Dong-Il Kim

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Chemical inhibition of α-mannosidase inFrontiers in parasitology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. In VitroJournal of microbiology and biotechnology · 2021
    Article
  17. Effects of Kifunensine on Production andInternational journal of molecular sciences · 2020
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hong-Yeol ChoiDepartment of Biological Engineering, Inha University, 100 Inha-ro, Nam-gu, Incheon, 22212, Republic of Korea.
Heajin ParkBiotherapeutics and Glycomics Laboratory, College of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06944, Republic of Korea.
Jong Kwang HongBioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01, Singapore, 138668, Singapore.
Sun-Dal KimDepartment of Biological Engineering, Inha University, 100 Inha-ro, Nam-gu, Incheon, 22212, Republic of Korea.
Jun-Young KwonDepartment of Biological Engineering, Inha University, 100 Inha-ro, Nam-gu, Incheon, 22212, Republic of Korea.
SeungKwan YouBiotherapeutics and Glycomics Laboratory, College of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06944, Republic of Korea.
Jonghye DoBiotherapeutics and Glycomics Laboratory, College of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06944, Republic of Korea.
Dong-Yup LeeBioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01, Singapore, 138668, Singapore.
Ha Hyung KimBiotherapeutics and Glycomics Laboratory, College of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06944, Republic of Korea. hahyung@cau.ac.kr.
Dong-Il KimDepartment of Biological Engineering, Inha University, 100 Inha-ro, Nam-gu, Incheon, 22212, Republic of Korea. kimdi@inha.ac.kr.

Funding

National Research Foundation of Korea (NRF) NRF-2013M3A9B6075887
6 · The paper itself

Abstract

Glycoengineering of plant expression systems is a prerequisite for the production of biopharmaceuticals that are compatible with animal-derived glycoproteins. Large amounts of high-mannose glycans such as Man

Indexed as

Alkaloidsalpha-GlucosidasesCells, CulturedEnzyme InhibitorsGlycosylationHumansMannoseMannosidasesOryzaPlants, Genetically ModifiedPolysaccharidesSwainsonineAlkaloidsalpha-GlucosidasesEnzyme InhibitorsGAA protein, humankifunensineMannoseMannosidasesPolysaccharidesSwainsonine

Identifiers

PMID30382146
PMCPMC6208381

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.