ArticleScientific reports2018
Bacillus megaterium adapts to acid stress condition through a network of genes: Insight from a genome-wide transcriptome analysis.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Comparative Genomic, Metabolic and Transcriptomic Profiling of Bacterial Isolates Reveals Strain-Specific Adaptation and Safety Traits.International journal of molecular sciences · 2026Article
- Zinc solubilizing rhizobacteria as bioinoculant for turmeric: transcriptomic insights into acid stress adaptation, zinc mobilization and growth promotion.World journal of microbiology & biotechnology · 2025Article
- Metal tolerance and recovery mechanisms of Priestia sp. Mn7 under pH 1.5.Extremophiles : life under extreme conditions · 2025Article
- Cellulase Production by Ultraviolet-Derived MutantInternational journal of molecular sciences · 2025Article
- Biodegradation of aflatoxin in dried figs.World journal of microbiology & biotechnology · 2025Article
- Genomic Insights and Plant Growth-Promoting Characterization ofPlants (Basel, Switzerland) · 2025Article
- Article
- Methods for studying microbial acid stress responses: from molecules to populations.FEMS microbiology reviews · 2024Review
- Priestia aryabhattai MBM3-Mediated Enhancement of Sulphur Metabolism in Brassica campestris.Current microbiology · 2024Article
- An oxalate decarboxylase-like cupin domain containing protein is involved in imparting acid stress tolerance in Bacillus amyloliquefaciens MBNC.World journal of microbiology & biotechnology · 2024Article
- Genomic analysis of acid tolerance genes and deciphering the function ofFrontiers in microbiology · 2024Article
- Bacillus megaterium HgT21: a Promising Metal Multiresistant Plant Growth-Promoting Bacteria for Soil Biorestoration.Microbiology spectrum · 2022Article
- Effects of Feeding 5-Aminolevulinic Acid on Iron Status in Weaned Rats from the Female Rats during Gestation and Lactation.Animals : an open access journal from MDPI · 2022Article
- Effect of Plant Preservative MixturePlants (Basel, Switzerland) · 2022Article
- Bio-Priming of Soybean withPlants (Basel, Switzerland) · 2022Article
- Proline confers acid stress tolerance to Bacillus megaterium G18.Scientific reports · 2022Article
- Comprehensive Transcriptomic Analysis of Heterotrophic Nitrifying BacteriumMicroorganisms · 2022Article
- Acid tolerant bacterium Bacillus amyloliquefaciens MBNC retains biocontrol efficiency against fungal phytopathogens in low pH.Archives of microbiology · 2022Article
- Production of polyhydroxyalkanoates (PHAs) byBioengineered · 2021Article
- A pH-Dependent Gene Expression Enables Bacillus amyloliquefaciens MBNC to Adapt to Acid Stress.Current microbiology · 2021Article
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Authors and funding
7 authors.
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Abstract
RNA-seq analysis of B. megaterium exposed to pH 7.0 and pH 4.5 showed differential expression of 207 genes related to several processes. Among the 207 genes, 11 genes displayed increased transcription exclusively in pH 4.5. Exposure to pH 4.5 induced the expression of genes related to maintenance of cell integrity, pH homeostasis, alternative energy generation and modification of metabolic processes. Metabolic processes like pentose phosphate pathway, fatty acid biosynthesis, cysteine and methionine metabolism and synthesis of arginine and proline were remodeled during acid stress. Genes associated with oxidative stress and osmotic stress were up-regulated at pH 4.5 indicating a link between acid stress and other stresses. Acid stress also induced expression of genes that encoded general stress-responsive proteins as well as several hypothetical proteins. Our study indicates that a network of genes aid B. megaterium G18 to adapt and survive in acid stress condition.
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