ArticleUltrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology2019
Increased Sylvian fissure angle as early sonographic sign of malformation of cortical development.
Article in Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- MRI-based assessment of fetal brain gyrification: Reliability across two methods.Neuroimage. Reports · 2026Article
- Deep learning assessment of fetal brain maturation on 3D ultrasound volumes in early-onset fetal growth restriction.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026Observational
- Doppler Assessment of the Fetal Brain Circulation.Diagnostics (Basel, Switzerland) · 2026Review
- Relationship between prenatal ultrasound signs and genetic abnormalities for fetal malformations of cortical development.Ultraschall in der Medizin (Stuttgart, Germany : 1980) · 2025Article
- A simple and quantitative ultrasonographic screening method for fetal Sylvian fissure abnormalities.European journal of medical research · 2025Article
- Third trimester diagnosis of a compound heterozygous QARS1 mutation based upon microcephaly and abnormal placenta.Case reports in perinatal medicine · 2025Article
- Sylvian fissure angle development on fetal MRI: 22-38 gestational weeks.Frontiers in neuroscience · 2025Article
- Prenatal diagnosis of intellectual disability, autosomal dominant 29 with a nonsense pathogenic variant inFrontiers in genetics · 2025Article
- Prenatal assessment of brain malformations on neuroimaging: an expert panel review.Brain : a journal of neurology · 2024Review
- Sonographic Cortical Development and Anomalies in the Fetus: A Systematic Review and Meta-Analysis.Biomedicines · 2024Review
- A Clinical Approach to Semiautomated Three-Dimensional Fetal Brain Biometry-Comparing the Strengths and Weaknesses of Two Diagnostic Tools: 5DCNS+Journal of clinical medicine · 2023Article
- Three-Dimensional Crystal Vue Imaging technology assessment of Sylvian fissures at 20-32+6 weeks' normal gestation.European radiology · 2023Article
- Applicability of a semiautomated volumetric approach (5D CNS+™) for detailed antenatal reconstruction of abnormal fetal CNS anatomy.BMC medical imaging · 2022Article
- Superficial anatomy of the neonatal cerebrum - an ultrasonographic roadmap.Pediatric radiology · 2021Review
- Validation of a semiautomated volumetric approach for fetal neurosonography using 5DCNS+ in clinical data from > 1100 consecutive pregnancies.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
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11 authors.
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Abstract
objectiveTo evaluate Sylvian fissure development by assessing Sylvian fissure angles in fetuses with malformation of cortical development (MCD).
methodsThis was a retrospective study of 22 fetuses with MCD. Cases with a stored three-dimensional (3D) brain volume acquired at 18 + 0 to 30 + 6 weeks of gestation at an ultrasound-based research clinic between January 2010 and December 2017 were identified through a database. Of the 22 fetuses, seven had an extracranial abnormality, such as cardiac, renal, gastrointestinal and/or digital anomalies, and five had a minor abnormality such as micrognathia, low-set ears and/or single umbilical artery. To confirm the final clinical diagnosis of brain abnormality, postmortem histological findings or prenatal or postnatal magnetic resonance images were used. For measurement of Sylvian fissure angle, an anterior coronal plane of the fetal brain on transvaginal 3D volume multiplanar imaging was visualized as a single image from the three orthogonal views. The right and left Sylvian fissure angles were measured between a horizontal reference line (0°) and a line drawn along the upper side of the respective Sylvian fissure. The Sylvian fissure angle on both sides was plotted on the graphs of the reference ranges for gestational age in weeks.
resultsIn 21 (95.5%; 95% CI, 86.8-100.0%) of 22 fetuses with MCD, the Sylvian fissure angle on one or both sides was larger than the 90
conclusionsThis study has shown that the Sylvian fissures, as defined by the Sylvian fissure angle, have delayed development in most MCD cases prior to the diagnosis of the condition. The Sylvian fissure angle may potentially be a strong indicator for the subsequent development of cortical malformation, before the time point at which the gyri and sulci become obvious on the fetal brain surface. Further research is required to validate these findings. © 2018 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of the International Society of Ultrasound in Obstetrics and Gynecology.
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