Evidence map›Paper›PMID 30381744›Full record

ArticleAsian-Australasian journal of animal sciences2019

Effects of coated cysteamine hydrochloride on muscle fiber characteristics and amino acid composition of finishing pigs.

Miaomiao Bai, Hongnan Liu, Kang Xu, Rong Yu, Abimbola Oladele Oso, Jinping Deng, Yulong Yin

Open access · goldAbstract read
In one paragraph

Article in Asian-Australasian journal of animal sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Miaomiao BaiScientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Breeding of Livestock and Poultry, Key Laboratory of Agro-ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China.ORCID 0000-0001-6984-0225
Hongnan LiuScientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Breeding of Livestock and Poultry, Key Laboratory of Agro-ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China.ORCID 0000-0002-5710-8624
Kang XuScientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Breeding of Livestock and Poultry, Key Laboratory of Agro-ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China.ORCID 0000-0002-8568-1540
Rong YuHangzhou King Techina Technology Company Academician Expert Workstation, Hangzhou King Techina Technology Co., Ltd., Hangzhou 311107, China.ORCID 0000-0001-6861-8737
Abimbola Oladele OsoDepartment of Animal Nutrition, College of Animal Science and Livestock Production, Federal University of Agriculture, Abeokuta PMB 2240, Nigeria.ORCID 0000-0001-9107-0933
Jinping DengCollege of Animal Science, South China Agricultural University, Guangzhou, Guangdong 510642, China.ORCID 0000-0002-8964-9986
Yulong YinScientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Breeding of Livestock and Poultry, Key Laboratory of Agro-ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China.ORCID 0000-0001-6112-6975
South China Agricultural University · CNInstitute of Subtropical Agriculture · CNFederal University of Agriculture · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This experiment was designed to determine the effects of coated cysteamine hydrochloride (CC) on muscle fiber characteristics, amino acid composition and transporters gene expression in the longissimus dorsi muscle (LDM) of finishing pigs. Methods: Two hundred and sixteen Duroc/Landrace/Yorkshire cross-bred male finishing pigs were fed with a corn-soybean basal diet supplemented with 0, 70 and 140 mg/kg cysteamine. Each group contained eight replicates of nine pigs per replicate. After 29 days, one pig was randomly selected from each replicate and slaughtered. Blood and LDM samples were collected and analyzed. Results: The results showed that supplemental dietary CC increased (P < 0.05) the muscle fiber density. And CC supplementation also up-regulated (P < 0.05) the expression of MyHC1 and MyHC2x mRNA levels, and down-regulated (P < 0.05) MyHC2b expression in the LDM. Additionally, supplemental dietary CC reduced (P < 0.05) the concentration of total cholesterol in the plasma and enhanced (P < 0.05) the concentrations of essential amino acid and total amino acid in the LDM. The relative expression levels of CAT2, b0,+AT, and y+LAT1 were up-regulated (P < 0.05) in the LDM when pigs were fed with the dietary CC of 70 mg/kg. Conclusion: Cysteamine supplementation could increase fiber density and distribution of fiber types. It also improved the deposition of protein in the LDM by up-regulated the expression of amino acid transporters.

Indexed as

Amino AcidsCoated Cysteamine HydrochlorideFinishing PigsMuscle Fiber

Identifiers

PMID30381744
PMCPMC6722302
OpenAlexW2898102544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.