Evidence map›Paper›PMID 30381364›Full record

ArticleOpen biology2018

The past, present and future of protein-based materials.

Nadia C Abascal, Lynne Regan

Open access · goldAbstract read
In one paragraph

Article in Open biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 104 citations in OpenAlex.

  1. Article
  2. Article
  3. Design and Heterologous Production of Bagworm Silk-Inspired Proteins inComputational and structural biotechnology journal · 2026
    Article
  4. Review
  5. EnhancingApplied and environmental microbiology · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. X-Ray Visible Protein Scaffolds by Bulk Iodination.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Highly Hydrophobic Films of Engineered Silk Proteins by a Simple Deposition Method.Langmuir : the ACS journal of surfaces and colloids · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Nadia C AbascalDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.ORCID 0000-0001-7611-3835
Lynne ReganDepartment of Interdisciplinary Science, Centre for Synthetic and Systems Biology, Institute for Quantitative Biology, Biochemistry and Biotechnology, School of Biological Sciences, University of Edinburgh, Edinburgh, UK lynne.regan@ed.ac.uk.
University of Edinburgh · GBYale University · US

Funding

Designed proteins to study and modulate cellular processesR01GM118528 · NIGMS · YALE UNIVERSITY · PI MOCHRIE, SIMON · 2017 to 2020
$1.2M
NIGMS NIH HHS R01 GM118528NIH HHS GM118528
6 · The paper itself

Abstract

Protein-based materials are finding new uses and applications after millennia of impacting the daily life of humans. Some of the earliest uses of protein-based materials are still evident in silk and wool textiles and leather goods. Today, even as silks, wools and leathers are still be used in traditional ways, these proteins are now seen as promising materials for biomaterials, vehicles of drug delivery and components of high-tech fabrics. With the advent of biosynthetic methods and streamlined means of protein purification, protein-based materials-recombinant and otherwise-are being used in a host of applications at the cutting edge of medicine, electronics, materials science and even fashion. This commentary aims to discuss a handful of these applications while taking a critical look at where protein-based materials may be used in the future.

Indexed as

AnimalsBiocompatible MaterialsCollagenDrug CarriersElastinHumansHydrogelsInsect ProteinsRecombinant ProteinsSilkTissue EngineeringWoolBiocompatible MaterialsCollagenDrug CarriersElastinHydrogelsInsect ProteinsRecombinant ProteinsresilinSilkbiomaterialsdrug deliveryprotein-based materialsrecombinant proteins

Identifiers

PMID30381364
PMCPMC6223211
OpenAlexW2898910462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.