Evidence map›Paper›PMID 30381303›Full record

ArticleHaematologica2019

Phase I dose-escalation study of brentuximab-vedotin combined with dexamethasone, high-dose cytarabine and cisplatin, as salvage treatment in relapsed/refractory classical Hodgkin lymphoma: The HOVON/LLPC Transplant BRaVE study.

Anton Hagenbeek, Hans Mooij, Josée Zijlstra, Pieternella Lugtenburg, Gustaaf van Imhoff, Marcel Nijland, Sanne Tonino, Martin Hutchings, Marjolein Spiering, Roberto Liu and 2 more

Open access · goldAbstract readClinical Trial, Phase ILetterMulticenter Study
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Emerging therapeutic strategies for CD30-positive lymphomas.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Antibody-Drug Conjugates: The Last Decade.Pharmaceuticals (Basel, Switzerland) · 2020
    Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Anton HagenbeekDepartment of Hematology, Amsterdam UMC, University of Amsterdam, the Netherlands a.hagenbeek@amc.nl.
Hans MooijDepartment of Hematology, Amsterdam UMC, University of Amsterdam, the Netherlands.
Josée ZijlstraDepartment of Hematology, Amsterdam UMC, Vrije Universiteit, the Netherlands.
Pieternella LugtenburgDepartment of Hematology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Gustaaf van ImhoffDepartment of Hematology, University Medical Center Groningen, the Netherlands.
Marcel NijlandDepartment of Hematology, University Medical Center Groningen, the Netherlands.
Sanne ToninoDepartment of Hematology, Amsterdam UMC, University of Amsterdam, the Netherlands.
Martin HutchingsDepartment of Hematology, Rigshospitalet, Copenhagen University Hospital, Denmark.
Marjolein SpieringDepartment of Hematology, Amsterdam UMC, University of Amsterdam, the Netherlands.
Roberto LiuDepartment of Hematology, Amsterdam UMC, University of Amsterdam, the Netherlands.
Harm van TinterenBiometric Department, NKI-AVL, Amsterdam, the Netherlands.
Marie José KerstenDepartment of Hematology, Amsterdam UMC, University of Amsterdam, the Netherlands.
Amsterdam University Medical Centers · NLUniversity Medical Center Groningen · NLCopenhagen University Hospital · DKErasmus MC Cancer Institute · NLThe Netherlands Cancer Institute · NLUniversity of Amsterdam · NLVrije Universiteit Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Salvage TherapyAdultAntineoplastic Combined Chemotherapy ProtocolsBrentuximab VedotinCisplatinCytarabineDexamethasoneDisease-Free SurvivalFemaleHodgkin DiseaseHumansMaleMiddle AgedRecurrenceSurvival RateBrentuximab VedotinCisplatinCytarabineDexamethasone

Identifiers

PMID30381303
PMCPMC6442967
OpenAlexW2898828813

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.