Evidence map›Paper›PMID 30380981›Full record

ArticleHuman vaccines & immunotherapeutics2019

Hepatitis B seroprevalence in 10-25-year-olds in Mexico - the 2012 national health and nutrition survey (ENSANUT) results.

Hugo López-Gatell, Lourdes García-García, Gabriela Echániz-Avilés, Pablo Cruz-Hervert, María Olamendi-Portugal, Deyanira Castañeda-Desales, Miguel Ángel Sanchez-Alemán, Martin Romero-Martínez, Rodrigo DeAntonio, Maria Yolanda Cervantes-Apolinar and 2 more

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Evaluation of acute and chronic exposure to aflatoxin BEnvironmental science and pollution research international · 2020
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hugo López-Gatella Centro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública , Morelos , México.
Lourdes García-Garcíaa Centro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública , Morelos , México.
Gabriela Echániz-Avilésa Centro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública , Morelos , México.
Pablo Cruz-Herverta Centro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública , Morelos , México.
María Olamendi-Portugala Centro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública , Morelos , México.
Deyanira Castañeda-Desalesa Centro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública , Morelos , México.
Miguel Ángel Sanchez-Alemána Centro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública , Morelos , México.
Martin Romero-Martínezb Centro de Investigación sobre Evaluación y Encuestas, Instituto Nacional de Salud Pública , Morelos , México.
Rodrigo DeAntonioc GSK , Panama City , Panama.ORCID 0000-0003-2586-4115
Maria Yolanda Cervantes-Apolinarc GSK , Panama City , Panama.
Ricardo Cortes-Alcalád GSK , Mexico City , Mexico.ORCID 0000-0001-5600-6979
Celia Alpuche-Arandaa Centro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública , Morelos , México.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo estimate hepatitis B virus (HBV) seroprevalence from natural infection or vaccination in 10-25-year-olds in Mexico, using the 2012 National Health and Nutrition Survey (ENSANUT).

methodsRandomly selected serum samples (1,581) from adolescents and young adults, representative of 38,924,584 Mexicans, were analyzed to detect hepatitis B surface antigen (HBsAg), hepatitis B surface antibody (anti-HBs) and hepatitis B core antibody (anti-HBc). Weighted HBV seroprevalence in the Mexican population and association with sociodemographic variables were calculated.

resultsOverall weighted seroprevalence from natural infection (positive for anti-HBs and anti-HBc) was 0.23% (95% confidence interval [95% CI] 0.10-0.52). No HBsAg was detected, indicating no acute or chronic infection. Vaccine-derived immunity (positive ≥ 10.0 mIU/ml for anti-HBs and negative to anti-HBc) was 44.7% (95% CI: 40.2-49.4) overall; lower in persons aged 20-25 years (40.83%) than in persons aged 10-19 years (47.7%). Among the population analyzed, 54.2% (95% CI: 49.6-58.8) were seronegative to HBV (negative for all three markers) and no sociodemographic risk factors were identified.

conclusionsHBV seroprevalence from natural infection was low. Vaccination-induced immunity was higher among Mexican adolescents than young adults, possibly due to vaccination policies since 1999.

Indexed as

AdolescentAdultBiomarkersChildFemaleHepatitis BHepatitis B AntibodiesHepatitis B VaccinesHepatitis B virusHumansMaleMexicoNutrition SurveysSeroepidemiologic StudiesYoung AdultBiomarkersHepatitis B AntibodiesHepatitis B VaccinesadolescentsHepatitis BMexiconational health surveysseroprevalence

Identifiers

PMID30380981
PMCPMC6422518

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.