Evidence map›Paper›PMID 30380804›Full record

ArticleMolecules (Basel, Switzerland)2018

Comparative Gene Expression Analysis in WM164 Melanoma Cells Revealed That

Nadine Kretschmer, Alexander Deutsch, Christin Durchschein, Beate Rinner, Alexander Stallinger, Juan Carlos Higareda-Almaraz, Marcel Scheideler, Birgit Lohberger, Rudolf Bauer

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Autophagy Paradox: Strategizing Treatment Modality in Melanoma.Current treatment options in oncology · 2023
    Review
  4. Review
  5. Article
  6. Article
  7. Polyurethane Foam Rafts Supported In Vitro Cultures ofInternational journal of molecular sciences · 2021
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Nadine KretschmerInstitute of Pharmaceutical Sciences, Department of Pharmacognosy, University of Graz, Universitaetsplatz 4/1, 8010 Graz, Austria. nadine.kretschmer@uni-graz.at.
Alexander DeutschDepartment of Hematology, Internal Medicine, Medical University Graz, Auenbruggerplatz 15, 8036 Graz, Austria. alexander.deutsch@medunigraz.at.
Christin DurchscheinInstitute of Pharmaceutical Sciences, Department of Pharmacognosy, University of Graz, Universitaetsplatz 4/1, 8010 Graz, Austria. christin.durchschein@uni-graz.at.
Beate RinnerDepartment for Biomedical Research, Medical University Graz, Roseggerweg 48, 8036 Graz, Austria. beate.rinner@medunigraz.at.
Alexander StallingerDepartment for Biomedical Research, Medical University Graz, Roseggerweg 48, 8036 Graz, Austria. alexander.stallinger@medunigraz.at.
Juan Carlos Higareda-AlmarazInstitute for Diabetes and Cancer (IDC), Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany. juan.higareda@helmholtz-muenchen.de.ORCID 0000-0002-4043-8547
Marcel ScheidelerInstitute for Diabetes and Cancer (IDC), Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany. marcel.scheideler@helmholtz-muenchen.de.ORCID 0000-0003-4650-7387
Birgit LohbergerDepartment of Orthopedics and Trauma, Medical University of Graz, Auenbruggerplatz 5, 8036 Graz, Austria. birgit.lohberger@medunigraz.at.
Rudolf BauerInstitute of Pharmaceutical Sciences, Department of Pharmacognosy, University of Graz, Universitaetsplatz 4/1, 8010 Graz, Austria. rudolf.bauer@uni-graz.at.ORCID 0000-0002-0057-5547
Medical University of Graz · ATUniversity of Graz · ATHeidelberg University · DE

Funding

Austrian Science Fund P27505
6 · The paper itself

Abstract

Skin cancer is currently diagnosed as one in every three cancers. Melanoma, the most aggressive form of skin cancer, is responsible for 79% of skin cancer deaths and the incidence is rising faster than in any other solid tumor type. Previously, we have demonstrated that dimethylacrylshikonin (DMAS), isolated from the roots of

Indexed as

ApoptosisCell Line, TumorCell ProliferationGene Expression RegulationHumansMelanomaMembrane Potential, MitochondrialMitochondriaNaphthoquinonesReactive Oxygen SpeciesSignal Transductionbeta, beta-dimethylacrylshikoninNaphthoquinonesReactive Oxygen Speciesautophagymelanomamitochondrial membrane potentialp62ROS generationβ-β-dimethylacrylshikonin

Identifiers

PMID30380804
PMCPMC6278572
OpenAlexW2899284175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.