Evidence map›Paper›PMID 30380764›Full record

ReviewMarine drugs2018

Discovery Methodology of Novel Conotoxins from

Ying Fu, Cheng Li, Shuai Dong, Yong Wu, Dongting Zhangsun, Sulan Luo

Abstract readReview
In one paragraph

Review in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. In Silico Conotoxin Studies: Progress and Prospects.Molecules (Basel, Switzerland) · 2024
    Review
  11. Review
  12. Review
  13. Article
  14. Anti-Ovarian Cancer Conotoxins Identified fromMolecules (Basel, Switzerland) · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ying FuKey Laboratory of Tropical Biological Resources, Ministry of Education, Hainan University, Haikou 570228, China. fuying926@163.com.
Cheng LiKey Laboratory of Tropical Biological Resources, Ministry of Education, Hainan University, Haikou 570228, China. licheng_0111@163.com.
Shuai DongKey Laboratory of Tropical Biological Resources, Ministry of Education, Hainan University, Haikou 570228, China. dongshuai_1024@163.com.
Yong WuKey Laboratory of Tropical Biological Resources, Ministry of Education, Hainan University, Haikou 570228, China. wys211@163.com.ORCID 0000-0002-2742-9013
Dongting ZhangsunKey Laboratory of Tropical Biological Resources, Ministry of Education, Hainan University, Haikou 570228, China. zhangsundt@163.com.
Sulan LuoKey Laboratory for Marine Drugs of Haikou, Hainan University, Haikou 570228, China. luosulan2003@163.com.ORCID 0000-0002-9358-5970

Funding

Changjiang Scholars and Innovative Research Team in University Grant IRT_15R15National Natural Science Foundation of China 31760249National Natural Science Foundation of China 81660585Natural Science Foundation of Hainan Province 817001
6 · The paper itself

Abstract

Cone snail venoms provide an ideal resource for neuropharmacological tools and drug candidates discovery, which have become a research hotspot in neuroscience and new drug development. More than 1,000,000 natural peptides are produced by cone snails, but less than 0.1% of the estimated conotoxins has been characterized to date. Hence, the discovery of novel conotoxins from the huge conotoxin resources with high-throughput and sensitive methods becomes a crucial key for the conotoxin-based drug development. In this review, we introduce the discovery methodology of new conotoxins from various

Indexed as

AnimalsCloning, MolecularConotoxinsConus SnailDrug DiscoveryHigh-Throughput Screening AssaysNeurotoxinsProteomicsConotoxinsNeurotoxinscrude venom purificationdiscoverygene cloningmethodologymulti-omicsnovel conotoxinsproteomicstranscriptomics

Identifiers

PMID30380764
PMCPMC6266589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.