Evidence map›Paper›PMID 30380731›Full record

ArticleInternational journal of molecular sciences2018

mRNA-Expression of

Markus Eckstein, Ralph Markus Wirtz, Matthias Gross-Weege, Johannes Breyer, Wolfgang Otto, Robert Stoehr, Danijel Sikic, Bastian Keck, Sebastian Eidt, Maximilian Burger and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. HER2 Expression, Test Deviations, and Their Impact on Survival in Metastatic Gastric Cancer: Results From the Prospective Multicenter VARIANZ Study.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Markus EcksteinInstitute of Pathology, University of Erlangen-Nuremberg, 91054 Erlangen, Germany. markus.eckstein@uk-erlangen.de.
Ralph Markus WirtzSTRATIFYER Molecular Pathology GmbH, 50935 Cologne, Germany. ralph.wirtz@stratifyer.de.
Matthias Gross-WeegeDepartment of Urology, University Medical Centre Mannheim, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany. matthias.gross-weege@umm.de.
Johannes BreyerDepartment of Urology, University of Regensburg, 93053 Regensburg, Germany. Johannes.breyer@ukr.de.
Wolfgang OttoDepartment of Urology, University of Regensburg, 93053 Regensburg, Germany. wolfgang.otto@ukr.de.
Robert StoehrInstitute of Pathology, University of Erlangen-Nuremberg, 91054 Erlangen, Germany. robert.stoehr@uk-erlangen.de.
Danijel SikicDepartment of Urology and Pediatric Urology, University Hospital Erlangen, 91058 Erlangen, Germany. danijel.sikic@uk-erlangen.de.
Bastian KeckDepartment of Urology and Pediatric Urology, University Hospital Erlangen, 91058 Erlangen, Germany. Bastian.keck@web.de.
Sebastian EidtInstitute of Pathology at the St Elisabeth Hospital Köln-Hohenlind, 50935 Cologne, Germany. Sebastian.eidt@stratifyer.de.
Maximilian BurgerDepartment of Urology, University of Regensburg, 93053 Regensburg, Germany. maximilian.burger@ukr.de.
Christian BolenzDepartment of Urology, University of Ulm, 89081 Ulm, Germany. Christian.Bolenz@uniklinik-ulm.de.
Katja NitschkeDepartment of Urology, University Medical Centre Mannheim, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany. katja.nitschke@medma.uni-heidelberg.de.
Stefan PorubskyDepartment of Pathology, University Medical Centre Mannheim, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany. Stefan.porubsky@medma.uni-heidelberg.de.
Arndt HartmannInstitute of Pathology, University of Erlangen-Nuremberg, 91054 Erlangen, Germany. arndt.hartmann@uk-erlangen.de.
Philipp ErbenDepartment of Urology, University Medical Centre Mannheim, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany. Philipp.Erben@medma.uni-heidelberg.de.ORCID 0000-0002-8279-7636
Heidelberg University · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity of Regensburg · DEUniversitätsklinikum Erlangen · DEUniversität Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, muscle-invasive bladder cancer (MIBC) has been subclassified by gene expression profiling, with a substantial impact on therapy response and patient outcome. We tested whether these complex molecular subtypes of MIBC can be determined by mRNA detection of keratin 5 (

Indexed as

Gene Expression Regulation, NeoplasticUrinary Bladder NeoplasmsDisease-Free SurvivalFemaleHumansImmunohistochemistryKeratin-20Keratin-5MaleNeoplasm ProteinsRNA, MessengerRNA, NeoplasmSurvival RateUrotheliumKeratin-20Keratin-5KRT20 protein, humanKRT5 protein, humanNeoplasm ProteinsRNA, MessengerRNA, NeoplasmBladder cancerKRT20KRT5molecular diagnosticsmolecular subtypingmuscle-invasive bladder cancer

Identifiers

PMID30380731
PMCPMC6274690
OpenAlexW2898862358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.