ArticleNanomaterials (Basel, Switzerland)2018
Exploring the Role of Nanoparticles in Enhancing Mechanical Properties of Hydrogel Nanocomposites.
Article in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 99 citations in OpenAlex.
- Strategies and Technologies for Comprehensive Characterization of Hydrogel-Based Materials in the Biomedical Field.Polymers · 2026Review
- Cyclodextrin-Silica Hybrid PEG Hydrogels: Mechanistic Coupling Between Stiffness, Relaxation, and Molecular Transport.Gels (Basel, Switzerland) · 2026Review
- Formulation of Hydrogel from Synthesized Silica-Reinforced Poly(Acrylamide/PVP) Polymer for Water Shut-Off in High-Temperature Reservoirs.ACS omega · 2026Article
- Programmed nanozyme hydrogel enabling spatiotemporal modulation of wound healing achieves skin regeneration after biofilm infection.Journal of nanobiotechnology · 2025Article
- Streamlined metal-based hydrogel facilitates stem cell differentiation, extracellular matrix homeostasis and cartilage repair in male rats.Nature communications · 2025Article
- Porous nanoparticles overcome the conventional stiffness-damping tradeoff in polymer nanocomposites.npj soft matter · 2025Article
- Role of metal nanomaterials in wound healing - a review.Frontiers in bioengineering and biotechnology · 2025Review
- Design strategy of hydrogel wound dressings based on oral special environment.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2024Article
- Review
- Preparation of High-Performance Barium Titanate Composite Hydrogels by Deep Eutectic Solvent-Assisted Frontal Polymerization.Materials (Basel, Switzerland) · 2024Article
- Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions.Signal transduction and targeted therapy · 2024Review
- Ultrasound Stimulation of Piezoelectric Nanocomposite Hydrogels Boosts Chondrogenic DifferentiationACS nano · 2024Article
- Porous silicon embedded in a thermoresponsive hydrogel for intranasal delivery of lipophilic drugs to treat rhinosinusitis.Journal of controlled release : official journal of the Controlled Release Society · 2023Article
- Article
- The Effect of Nano Zirconium Dioxide (ZrONanomaterials (Basel, Switzerland) · 2023Article
- Application of Silk-Fibroin-Based Hydrogels in Tissue Engineering.Gels (Basel, Switzerland) · 2023Review
- Modeling the Additive Effects of Nanoparticles and Polymers on Hydrogel Mechanical Properties Using Multifactor Analysis.Nanomaterials (Basel, Switzerland) · 2022Article
- Combined Effects of Radiative and Evaporative Cooling on Fruit Preservation under Solar Radiation: Sunburn Resistance and Temperature Stabilization.ACS applied materials & interfaces · 2022Article
- Nanotechnology for research and treatment of the intestine.Journal of nanobiotechnology · 2022Review
- Hybrid extracellular vesicles-liposome incorporated advanced bioink to deliver microRNA.Biofabrication · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past few decades, research studies have established that the mechanical properties of hydrogels can be largely impacted by the addition of nanoparticles. However, the exact mechanisms behind such enhancements are not yet fully understood. To further explore the role of nanoparticles on the enhanced mechanical properties of hydrogel nanocomposites, we used chemically crosslinked polyacrylamide hydrogels incorporating silica nanoparticles as the model system. Rheological measurements indicate that nanoparticle-mediated increases in hydrogel elastic modulus can exceed the maximum modulus that can be obtained through purely chemical crosslinking. Moreover, the data reveal that nanoparticle, monomer, and chemical crosslinker concentrations can all play an important role on the nanoparticle mediated-enhancements in mechanical properties. These results also demonstrate a strong role for pseudo crosslinking facilitated by polymer⁻particle interactions on the observed enhancements in elastic moduli. Taken together, our work delves into the role of nanoparticles on enhancing hydrogel properties, which is vital to the development of hydrogel nanocomposites with a wide range of specific mechanical properties.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.