ArticleCell reports2018
Alpha-Amino-Beta-Carboxy-Muconate-Semialdehyde Decarboxylase Controls Dietary Niacin Requirements for NAD
Open access · goldAbstract read
In one paragraph
Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 50 citations in OpenAlex.
- Nutrition Information Briefs - Niacin.Advances in nutrition (Bethesda, Md.) · 2026Article
- The kynurenine pathway storm in epilepsy: mechanisms and therapeutic implications.Acta epileptologica · 2026Review
- DeepMetabio-mCRC Screener: A Multi-Omics Deep Learning Framework for Early Risk Prediction and Biomarker Discovery in Colorectal Liver Metastasis.Computational and structural biotechnology journal · 2026Article
- ROS-responsive cellular vesicles with ferroptosis-targeting siACMSD delivery for acute kidney injury therapy.Theranostics · 2026Article
- Metabolic reprogramming in ischemic stroke: when glycolytic overdrive meets lipid storm.Cell death & disease · 2025Review
- NADNature metabolism · 2025Review
- Chronic Cellular NAD Depletion Activates a Viral Infection-Like Interferon Response Through Mitochondrial DNA Leakage.Aging cell · 2025Article
- Diverse Physiological Roles of Kynurenine Pathway Metabolites: Updated Implications for Health and Disease.Metabolites · 2025Review
- Analysis of the underlying mechanism ofPharmaceutical science advances · 2024Article
- The tryptophan metabolic pathway of the microbiome and host cells in health and disease.International immunology · 2024Review
- Regulation of and challenges in targeting NADNature reviews. Molecular cell biology · 2024Review
- A metabolic signature for NADSYN1-dependent congenital NAD deficiency disorder.The Journal of clinical investigation · 2024Article
- Inhibitors of NADInternational journal of molecular sciences · 2024Review
- NAD metabolism: Role in senescence regulation and aging.Aging cell · 2024Review
- Reproductive toxicology: keeping up with our changing world.Frontiers in toxicology · 2024Article
- Nicotinamide Adenine Dinucleotide in Aging Biology: Potential Applications and Many Unknowns.Endocrine reviews · 2023Review
- Systemic Activation of the Kynurenine Pathway in Graves Disease With and Without Ophthalmopathy.The Journal of clinical endocrinology and metabolism · 2023Article
- Kynurenine Pathway Metabolites as Potential Biomarkers in Chronic Pain.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Review
- Endogenous metabolism in endothelial and immune cells generates most of the tissue vitamin B3 (nicotinamide).iScience · 2022Article
Corrections and comments
- Commented on by
Authors and funding
14 authors at 6 institutions in 2 countries.
Laura PalzerDepartment of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84332, USA.
Jessica J BaderDepartment of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84332, USA; Utah Experimental Station, Utah State University, Logan, UT 84332, USA.
Frances AngelDepartment of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84332, USA.
Megan WitzelDepartment of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84332, USA.
Sydney BlaserDepartment of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84332, USA.
Alexis McNeilDepartment of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84332, USA.
Miles K WanderseeDepartment of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84332, USA.
N Adrian LeuDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Christopher J LengnerDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Clara E ChoDepartment of Nutrition, Dietetics, and Food Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84332, USA.
Kevin D WelchPoisonous Plant Research Laboratory, USDA Agricultural Research Service, Logan, UT 84332, USA.
James B KirklandUniversity of Guelph, Guelph, ON N1G 2WI, Canada.
Ralph G MeyerDepartment of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84332, USA; Utah Experimental Station, Utah State University, Logan, UT 84332, USA.
Mirella L Meyer-FiccaDepartment of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT 84332, USA. Electronic address: mirella.meyer@usu.edu.
Utah State University · USAgricultural Research Service · USCalifornia Institute for Regenerative Medicine · USExperimental Station · USUniversity of Guelph · CAUniversity of Pennsylvania · US
Funding
Vitamin B3 requirements of the TestisR15HD100970 · NICHD · UTAH STATE UNIVERSITY · PI MEYER, RALPH G · 2020 to 2020
$363kNICHD NIH HHS R15 HD100970
Abstract
NAD
Indexed as
DietAcetyl Coenzyme AAnimalsCarboxy-LyasesDoxycyclineHumansLactatesLiverMice, Inbred C57BLNADNADPNiacinOxidation-ReductionPyruvatesWeight LossAcetyl Coenzyme Aaminocarboxymuconate-semialdehyde decarboxylaseCarboxy-LyasesDoxycyclineLactatesNADNADPNiacinPyruvatesACMSDkynureninemetabolismNADNADPniacinnicotinamidenicotinic acidtryptophanvitamin B3
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.