Evidence map›Paper›PMID 30380140›Full record

ArticleJournal of surgical oncology2018

Impact of delayed care on surgical management of patients with gastric cancer in a low-resource setting.

Allison N Martin, Allison Silverstein, Robinson Ssebuufu, Joseph Lule, Pacifique Mugenzi, Alexandra Fehr, Tharcisse Mpunga, Lawrence N Shulman, Paul H Park, Ainhoa Costas-Chavarri

Abstract readMulticenter Study
In one paragraph

Article in Journal of surgical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Allison N MartinDepartment of Surgery, University of Virginia, Charlottesville, Virginia.ORCID http://orcid.org/0000-0002-9216-0647
Allison SilversteinDepartment of Plastic Surgery, Boston Children's Hospital, Boston, Massachusetts.
Robinson SsebuufuDepartment of Surgery, Centre Hospitalier Universitaire de Butare, Butare, Rwanda.
Joseph LuleDepartment of Surgery, Rwanda Military Hospital, Kigali, Rwanda.
Pacifique MugenziDepartment of Surgery, Rwanda Military Hospital, Kigali, Rwanda.
Alexandra FehrPartners In Health/Inshuti Mu Buzima, Kigali, Rwanda.
Tharcisse MpungaMinistry of Health, Kigali, Rwanda.
Lawrence N ShulmanPartners In Health/Inshuti Mu Buzima, Kigali, Rwanda.
Paul H ParkProgram in Global Surgery and Social Change, Harvard Medical School, Boston, Massachusetts.
Ainhoa Costas-ChavarriDepartment of Plastic Surgery, Boston Children's Hospital, Boston, Massachusetts.

Funding

Vanderbilt-Emory-Cornell-Duke Global Health Fellowship Consortium-Expanding Diversity for Global Equity (EDGE)D43TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALIYU, MUKTAR HASSAN, HEIMBURGER, DOUGLAS CORBETT · 2017 to 2021
$6.3M
Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)R25TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HEIMBURGER, DOUGLAS CORBETT, VERMUND, STEN H. · 2012 to 2016
$6.3M
Postdoctoral Training Grant for MDs in Surgical Oncology ResearchT32CA163177 · NCI · UNIVERSITY OF VIRGINIA · PI Craig Lee Slingluff, Allan Tsung · 2011 to 2026
$4.6M
FIC NIH HHS D43 TW009337FIC NIH HHS R25 TW009337Fogarty International Center 5R25TW009337-06National Cancer Institute CA163177NCI NIH HHS T32 CA163177
6 · The paper itself

Abstract

backgroundGastric cancer is the fifth most common cancer in Eastern Africa. Diagnostic delays in low-resource countries result in advanced disease presentation. We describe perioperative management of gastric cancer in Rwanda.

methodsA retrospective review of records at three hospitals was performed to identify gastric adenocarcinoma cases from January 2012 to June 2016. Multiple perioperative and tumor-related variables were collected. Descriptive and bivariate analyses were performed.

resultsThe final analysis included 229 patients with gastric cancer. Median age was 58 years (interquartile range [IQR] 49-65) and 49.6% were female (n = 114). Patients reported symptoms (ie, weight loss, epigastric pain) for a median time of 12 months (IQR 7.5-24). On presentation, 18.8% ( n = 43) had gastric outlet obstruction; 13.5% ( n = 31) had a palpable mass. Fifty-one percent ( n = 117) underwent an operation; of these, 74% ( n = 86) received gastrojejunostomy or were inoperable; and 29% ( n = 34) underwent curative resection. Palliative care referrals were made for 9% ( n = 20). Pathology reports were available for 190 patients (83.0%). Only 11.3% ( n = 26) had Helicobacter pylori ( H. pylori) testing of which 65.4% tested positive ( n = 17).

conclusionsA majority of patients presented with advanced disease. Very few patients had a curative resection. Significant advances in diagnosis and treatment are needed to improve the care of gastric cancer patients in Rwanda.

Indexed as

AdenocarcinomaCohort StudiesDigestive System Surgical ProceduresFemaleHelicobacter InfectionsHelicobacter pyloriHumansMaleMiddle AgedNeoplasm StagingRetrospective StudiesRwandaStomach NeoplasmsTime-to-TreatmentTreatment OutcomeAfricacancer surgerygastric cancerlow resourceRwanda

Identifiers

PMID30380140
PMCPMC6250579

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.