Evidence map›Paper›PMID 30380072›Full record

ArticleNucleic acids research2019

LncRNA2Target v2.0: a comprehensive database for target genes of lncRNAs in human and mouse.

Liang Cheng, Pingping Wang, Rui Tian, Song Wang, Qinghua Guo, Meng Luo, Wenyang Zhou, Guiyou Liu, Huijie Jiang, Qinghua Jiang

Abstract read
In one paragraph

Article in Nucleic acids research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 184 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
184citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

184 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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124 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Liang ChengCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, China.
Pingping WangCenter for Bioinformatics, School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China.
Rui TianCenter for Bioinformatics, School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China.
Song WangDepartment of Radiology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Qinghua GuoCenter for Bioinformatics, School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China.
Meng LuoCenter for Bioinformatics, School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China.
Wenyang ZhouCenter for Bioinformatics, School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China.
Guiyou LiuCenter for Bioinformatics, School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China.
Huijie JiangDepartment of Radiology, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Qinghua JiangCenter for Bioinformatics, School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) play crucial roles in regulating gene expression, and a growing number of researchers have focused on the identification of target genes of lncRNAs. However, no online repository is available to collect the information on target genes regulated by lncRNAs. To make it convenient for researchers to know what genes are regulated by a lncRNA of interest, we developed a database named lncRNA2Target to provide a comprehensive resource of lncRNA target genes in 2015. To update the database this year, we retrieved all new lncRNA-target relationships from papers published from 1 August 2014 to 30 April 2018 and RNA-seq datasets before and after knockdown or overexpression of a specific lncRNA. LncRNA2Target database v2.0 provides a web interface through which its users can search for the targets of a particular lncRNA or for the lncRNAs that target a particular gene, and is freely accessible at http://123.59.132.21/lncrna2target.

Indexed as

Databases, Nucleic AcidGene Expression RegulationRNA InterferenceAnimalsComputational BiologyHumansMiceRNA, Long NoncodingSoftwareUser-Computer InterfaceWeb BrowserRNA, Long Noncoding

Identifiers

PMID30380072
PMCPMC6323902

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.