Evidence map›Paper›PMID 30379941›Full record

ArticlePloS one2018

Axon numbers and landmarks of trigeminal donor nerves for corneal neurotization.

Eva Györi, Chieh-Han John Tzou, Wolfgang J Weninger, Lukas Reissig, Ursula Schmidt-Erfurth, Christine Radtke, Roman Dunavoelgyi

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Eva GyöriDivision of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-6234-0284
Chieh-Han John TzouDivision of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-3903-801X
Wolfgang J WeningerDivision of Anatomy, Medical University of Vienna, Vienna, Austria.
Lukas ReissigDivision of Anatomy, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-5833-8176
Ursula Schmidt-ErfurthDepartment of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.
Christine RadtkeDivision of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria.
Roman DunavoelgyiDepartment of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.
Medical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCorneal anesthesia leads to chronic corneal injury. This anatomical study characterizes the donor nerve branches of the supratrochlear and supraorbital nerves used for corneal neurotization.

methodsIn 13 non-embalmed cadavers, the supratrochlear and supraorbital nerves were dissected and distances to anatomical landmarks measured. Cross-sections of supratrochlear and supraorbital donor nerves were harvested and histomorphometrically analyzed to assess the number of myelinated axons.

resultsThe donor axon counts were 3146 ± 1069.9 for the supratrochlear and 1882 ± 903 for the supraorbital nerve distal to the supraorbital notch. The supratrochlear nerve was dissected on the medial upper eyelid 2 cm lateral to the facial midline and the branch of the supraorbital nerve 1 cm medial to the mid-pupillary line.

conclusionThe supraorbital and supratrochlear branches of the trigeminal nerve are potent donor nerves for corneal neurotization in the treatment of neuropathic keratopathy and can be reliably dissected using anatomical landmarks.

Indexed as

AxonsCorneaCorneal DiseasesHumansNerve TransferTrigeminal Nerve

Identifiers

PMID30379941
PMCPMC6209308
OpenAlexW2898986367

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.