ArticleAmerican journal of physiology. Heart and circulatory physiology2019
Bromine inhalation mimics ischemia-reperfusion cardiomyocyte injury and calpain activation in rats.
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Article in American journal of physiology. Heart and circulatory physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
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Who cites it
20 citing papers in PubMed, 28 citations in OpenAlex.
- The lung-brain axis: elucidating the mechanisms of pulmonary-driven neurological disorders.Journal of neuroinflammation · 2026Review
- Inhaled Halogen-Induced Oxidative Renal Damage and Dysfunction: A Lung Heart Kidney Axis.Comprehensive Physiology · 2026Article
- Myocardial SERCA2 Protects Against Cardiac Damage and Dysfunction Caused by Inhaled Bromine.The Journal of pharmacology and experimental therapeutics · 2024Article
- Epigenetic mechanisms of alveolar macrophage activation in chemical-induced acute lung injury.Frontiers in immunology · 2024Review
- Lipid biology of plasmalogen-derived halolipids: Signature molecules of myeloperoxidase and eosinophil peroxidase activity.Redox biochemistry and chemistry · 2023Article
- Halogenation Activity of Mammalian Heme Peroxidases.Antioxidants (Basel, Switzerland) · 2022Review
- Sex differences in cardiopulmonary effects of acute bromine exposure.Toxicology research · 2021Article
- Halogen-Induced Chemical Injury to the Mammalian Cardiopulmonary Systems.Physiology (Bethesda, Md.) · 2021Review
- Behavioral and Neuronal Effects of Inhaled Bromine Gas: Oxidative Brain Stem Damage.International journal of molecular sciences · 2021Article
- Halogen gas exposure: toxic effects on the parturient.Toxicology mechanisms and methods · 2021Article
- Chronic cardiac structural damage, diastolic and systolic dysfunction following acute myocardial injury due to bromine exposure in rats.Archives of toxicology · 2021Article
- Echocardiographic, Biochemical, and Electrocardiographic Correlates Associated With Progressive Pulmonary Arterial Hypertension.Frontiers in cardiovascular medicine · 2021Article
- Hyaluronan and halogen-induced airway hyperresponsiveness and lung injury.Annals of the New York Academy of Sciences · 2020Review
- Circulating and tissue biomarkers as predictors of bromine gas inhalation.Annals of the New York Academy of Sciences · 2020Article
- Hemodynamic assessment of diastolic function for experimental models.American journal of physiology. Heart and circulatory physiology · 2020Review
- Upregulation of airway smooth muscle calcium-sensing receptor by low-molecular-weight hyaluronan.American journal of physiology. Lung cellular and molecular physiology · 2020Article
- Vascular Endothelial Growth Factor-121 Administration Mitigates Halogen Inhalation-Induced Pulmonary Injury and Fetal Growth Restriction in Pregnant Mice.Journal of the American Heart Association · 2020Article
- Phosgene inhalation causes hemolysis and acute lung injury.Toxicology letters · 2019Article
- Calpain in the cleavage of alpha-synuclein and the pathogenesis of Parkinson's disease.Progress in molecular biology and translational science · 2019Review
- Article
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 2 countries.
Shama AhmadDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham , Birmingham, Alabama.ORCID 0000-0003-1049-5054
Juan Xavier Masjoan JuncosDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham , Birmingham, Alabama.
Aftab AhmadDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham , Birmingham, Alabama.ORCID 0000-0003-0686-0987
Ahmed ZakyDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham , Birmingham, Alabama.
Chih-Chang WeiDivision of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham , Birmingham, Alabama.
Wayne E BradleyDivision of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham , Birmingham, Alabama.
Iram ZafarDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham , Birmingham, Alabama.
Pamela PowellDivision of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham , Birmingham, Alabama.
Nithya MariappanDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham , Birmingham, Alabama.
Nilam VetalDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham , Birmingham, Alabama.
William E LouchInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo , Oslo , Norway.
David A FordDepartment of Biochemistry and Molecular Biology and Center for Cardiovascular Research, Saint Louis University , St. Louis, Missouri.
Stephen F DoranDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham , Birmingham, Alabama.
Sadis MatalonDepartment of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham , Birmingham, Alabama.
Louis J Dell'ItaliaDivision of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham , Birmingham, Alabama.
University of Alabama at Birmingham · USOslo University Hospital · NOSaint Louis University · US
Funding
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5MBromine Inhalation Induced Lung Injury: Novel Mechanisms and Treatment StrategiesU01ES026458 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MATALON, SADIS · 2015 to 2019
$3.9MExtracellular RNA as therapeutic target after toxic chemical inhalationU01ES025069 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AHMAD, AFTAB · 2014 to 2019
$2.5MHypoxic factors in pulmonary hypertensionR01HL114933 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI AHMAD, AFTAB · 2014 to 2018
$1.5MTargeting cardiopulmonary calpains to mitigate toxicity of halogen gases.U01ES028182 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AHMAD, SHAMA, DELL'ITALIA, LOUIS J. · 2017 to 2019
$1.3MNHLBI NIH HHS R01 HL114933NIDDK NIH HHS P30 DK079626NIEHS NIH HHS U01 ES025069NIEHS NIH HHS U01 ES026458NIEHS NIH HHS U01 ES028182
Abstract
Halogens are widely used, highly toxic chemicals that pose a potential threat to humans because of their abundance. Halogens such as bromine (Br
Indexed as
Administration, InhalationAnimalsBiomarkersBromineCalpainCells, CulturedHemodynamicsMaleMitochondria, HeartMyocardial ContractionMyocardial Reperfusion InjuryMyocytes, CardiacRatsRats, Sprague-DawleySarcoplasmic Reticulum Calcium-Transporting ATPasesVentricular DysfunctionBiomarkersBromineCalpainSarcoplasmic Reticulum Calcium-Transporting ATPasescalciumcalpainscardiachalogenneutrophilsarco(endo)plasmic reticulum Ca-ATPase
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Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.