Evidence map›Paper›PMID 30379566›Full record

ArticleThe British journal of radiology2019

Reirradiation for isolated local recurrence of prostate cancer: Mono-institutional series of 64 patients treated with salvage stereotactic body radiotherapy (SBRT).

Barbara Alicja Jereczek-Fossa, Damaris Patricia Rojas, Dario Zerini, Cristiana Fodor, Anna Viola, Giuseppe Fanetti, Stefania Volpe, Rosa Luraschi, Alessia Bazani, Elena Rondi and 12 more

Abstract read
In one paragraph

Article in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Stereotactic body radiotherapy (SBRT) re-irradiation for local failures following radical prostatectomy and post-operative radiotherapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024
    Article
  11. Stereotactic reirradiation with CyberknifeLa Radiologia medica · 2023
    Article
  12. Review
  13. Article
  14. Linac-based stereotactic salvage reirradiation for intraprostatic prostate cancer recurrence: toxicity and outcomes.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Barbara Alicja Jereczek-Fossa1 Division of Radiation Oncology, European Institute of Oncology IRCCS , Milan , Italy.
Damaris Patricia Rojas1 Division of Radiation Oncology, European Institute of Oncology IRCCS , Milan , Italy.ORCID http://orcid.org/0000-0001-8074-5042
Dario Zerini1 Division of Radiation Oncology, European Institute of Oncology IRCCS , Milan , Italy.
Cristiana Fodor1 Division of Radiation Oncology, European Institute of Oncology IRCCS , Milan , Italy.
Anna Viola1 Division of Radiation Oncology, European Institute of Oncology IRCCS , Milan , Italy.
Giuseppe Fanetti1 Division of Radiation Oncology, European Institute of Oncology IRCCS , Milan , Italy.
Stefania Volpe1 Division of Radiation Oncology, European Institute of Oncology IRCCS , Milan , Italy.
Rosa Luraschi3 Unit of Medical Physics, European Institute of Oncology IRCCS , Milan , Italy.
Alessia Bazani3 Unit of Medical Physics, European Institute of Oncology IRCCS , Milan , Italy.
Elena Rondi3 Unit of Medical Physics, European Institute of Oncology IRCCS , Milan , Italy.
Federica Cattani3 Unit of Medical Physics, European Institute of Oncology IRCCS , Milan , Italy.
Andrea Vavassori1 Division of Radiation Oncology, European Institute of Oncology IRCCS , Milan , Italy.
Cristina Garibaldi4 Radiation Research Unit, European Institute of Oncology IRCCS , Milano , Italy.
Sarah Alessi5 Division of Radiology, European Institute of Oncology IRCCS , Milan , Italy.
Paola Pricolo5 Division of Radiology, European Institute of Oncology IRCCS , Milan , Italy.
Giuseppe Petralia5 Division of Radiology, European Institute of Oncology IRCCS , Milan , Italy.
Gabriele Cozzi6 Division of Urology, European Institute of Oncology IRCCS , Milan , Italy.
Ottavio De Cobelli6 Division of Urology, European Institute of Oncology IRCCS , Milan , Italy.
Gennaro Musi6 Division of Urology, European Institute of Oncology IRCCS , Milan , Italy.
Roberto Orecchia7 Scientific Directorate, European Institute of Oncology IRCCS , Milan , Italy.
Giulia Marvaso1 Division of Radiation Oncology, European Institute of Oncology IRCCS , Milan , Italy.
Delia Ciardo1 Division of Radiation Oncology, European Institute of Oncology IRCCS , Milan , Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objective: To evaluate high-precision external beam reirradiation (re-EBRT) for local relapse of prostate cancer (PCa) after radiotherapy.

methods: This retrospective study included patients with biochemical failure and evidence of isolated local recurrence of PCa after radical/salvage EBRT or brachytherapy that received salvage stereotactic body radiation therapy (SBRT, re-EBRT). Biopsy was not mandatory if all diagnostic elements were univocal (prostate specific antigen evolution, choline-positron emission tomography or magnetic resonance imaging). Salvage SBRT (re-EBRT) was delivered with image-guided radiation therapy (RapidArc®, VERO® and CyberKnife®).

results: Data of 64 patients were included, median age at salvage SBRT was 73.2 years, median pre-salvage SBRT prostate specific antigen was 3.89  ng ml

conclusions: Salvage SBRT (re-EBRT) for isolated local PCa recurrence is a safe, feasible and noninvasive salvage treatment. Further investigation is warranted to define the optimal patient selection, dose and volume parameters. ADVANCES IN KNOWLEDGE:: Salvage SBRT reirradiation for the locally recurrent PCa offer a satisfactory tumor control and excellent toxicity profile, if BED ≥130 Gy is administered.

Indexed as

RadiosurgeryRe-IrradiationAgedAged, 80 and overAndrogen AntagonistsBiopsyCombined Modality TherapyHumansMagnetic Resonance ImagingMaleMiddle AgedNeoplasm Recurrence, LocalPositron-Emission TomographyProgression-Free SurvivalProstate-Specific AntigenProstatic NeoplasmsAndrogen AntagonistsProstate-Specific Antigen

Identifiers

PMID30379566
PMCPMC6404844

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.