Trial reportSocial neuroscience2019
Oxytocin increases eye-gaze towards novel social and non-social stimuli.
Trial report in Social neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Tri-Phasic Model ofOxytocin (TRIO): A systematic conceptual review of oxytocin-related ERP research.Biological psychology · 2020Pooled it
- Null results of oxytocin and vasopressin administration on mentalizing in a large fMRI sample: evidence from a randomized controlled trial.Psychological medicine · 2023Trial
- Oral Administration of Oxytocin, Like Intranasal Administration, Decreases Top-Down Social Attention.The international journal of neuropsychopharmacology · 2022Trial
- Oxytocin enhances neural approach towards social and non-social stimuli of high personal relevance.Scientific reports · 2021Trial
- Eye-Tracking Reveals a Role of Oxytocin in Attention Allocation Towards Familiar Faces.Frontiers in endocrinology · 2021Trial
- The effect of intranasal oxytocin on visual processing and salience of human faces.Translational psychiatry · 2020Trial
- Oxytocin biases eye-gaze to dynamic and static social images and the eyes of fearful faces: associations with trait autism.Translational psychiatry · 2020Trial
- Natural variation in the oxytocin receptor gene predicts social observation in female prairie voles.bioRxiv : the preprint server for biology · 2025Article
- Complexity of the Hypothalamic Oxytocin System and its Involvement in Brain Functions and Diseases.Neuroscience bulletin · 2025Review
- How does oxytocin modulate human behavior?Molecular psychiatry · 2025Review
- From Oxytocin to Compassion: The Saliency of Distress.Biology · 2023Article
- Combinatorial approaches for treating neuropsychiatric social impairment.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Oro-mucosal administration of oxytocin using medicated lollipops alters social attention, similar to intranasal and lingual routes: Implications for therapeutic use.Frontiers in neuroscience · 2022Article
- The Role of Intranasal Oxytocin on Social Cognition: An Integrative Human Lifespan Approach.Current behavioral neuroscience reports · 2020Article
- Oxytocin makes inexperienced men more selective in their dating strategy.Comprehensive psychoneuroendocrinology · 2020Article
- Orally administered oxytocin alters brain activation and behaviors of pre-weaning mice.Hormones and behavior · 2020Article
- Oxytocin Facilitation of Emotional Empathy Is Associated With Increased Eye Gaze Toward the Faces of Individuals in Emotional Contexts.Frontiers in neuroscience · 2020Article
- Oxytocin Modulates the Cognitive Appraisal of the Own and Others Close Intimate Relationships.Frontiers in neuroscience · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
Research on oxytocin (OT) has revealed a substantial involvement of this neuropeptide in social cognition processes and attachment behavior. The rationale of the present project was to decipher the differential role of OT in basic social cognition processes towards non-erotic attachment stimuli vs. reproduction-related stimuli in human subjects. In a randomized double-blind repeated-measures cross-over design, N = 82 participants were investigated twice and received either intranasal OT or placebo at the first assessment followed by placebo or OT at second assessment. Participants were presented with standardized pictures of parent-child dyads, romantic couples engaging in non-erotic or explicit sexual activities, and non-social pictures while we assessed pupil dilation and eye focus on specific pre-defined areas of interest. Multilevel analyses suggest that during the initial presentation, OT increased pupil dilation towards all categories of stimuli and led the eye focus towards the eyes and body regions, followed by a strong decrease in pupil dilation and fixations at the second session. These carry-over effects indicate that hormonal treatment at an initial contact to social stimuli can determine how these stimuli are processed later. These results might have implications for OT as a treatment in interventions with repeated exposure to social material.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.