ArticleRevista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia2018
In silico analysis of transferable QepA variants and related chromosomal efflux pumps.
Article in Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed.
- Unusual and Unconsidered Mechanisms of Bacterial Resilience and Resistance to Quinolones.Life (Basel, Switzerland) · 2024Review
- Expression of the qepA1 gene is induced under antibiotic exposure.The Journal of antimicrobial chemotherapy · 2021Article
- Transferable Mechanisms of Quinolone Resistance from 1998 Onward.Clinical microbiology reviews · 2019Review
- Novel quinolone resistance determinant,Antimicrobial agents and chemotherapy · 2019Article
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Authors and funding
1 author.
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Abstract
objectiveThe present study aimed to detect the presence of undescribed QepA variants in GenBank records.
methodsThe DNA and amino acid sequences of QepA1 were compared with what is present in GenBank. Only annealings with a >80% identity were considered. No synthetic or partial sequences were included in the analyses.
resultsThe results showed the presence of 10 different QepA variants, 6 of them which were previously non-designated as specific allelic variants. In addition, high identity levels with chromosomal MSF efflux pumps belonging to microorganisms of the Pseudorhodoferax genus and other Comamonadaceae were detected.
conclusionsThe presence of undescribed QepA variants in GenBank is reported and the presence of related sequences among members of Burkholderiales order is described.
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Identifiers
30378393PMC6254477What OpenQuestion holds
Registered trials
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