SynthesisDiabetes/metabolism research and reviews2019
Resting heart rate and risk of type 2 diabetes: A prospective cohort study and meta-analysis.
Synthesis in Diabetes/metabolism research and reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 52 citations in OpenAlex.
- Association between physical function and type 2 diabetes risk in older adults: a longitudinal analysis from the KoGES-Anseong cohort.European geriatric medicine · 2026Article
- Article
- Nocturnal heart rate during sleep is associated with increased risk of type 2 diabetes mellitus in adults with obstructive sleep apnoea syndrome.Annals of medicine · 2025Article
- Association of maternal nocturnal heart rate and adverse pregnancy outcomes.Pregnancy (Hoboken, N.J.) · 2025Article
- Association between resting heart rate and prognosis in patients with gastric cancer.Scientific reports · 2025Article
- Classification and identification of risk factors for type 2 diabetes.World journal of diabetes · 2025Review
- AI Machine Learning-Based Diabetes Prediction in Older Adults in South Korea: Cross-Sectional Analysis.JMIR formative research · 2025Article
- Reduced heart rate response to exercise in patients with type 2 diabetes.Frontiers in cardiovascular medicine · 2025Article
- The association between resting heart rate and HbA1c-assessed glycemic control in patients with type 2 diabetes in Eastern China.Frontiers in endocrinology · 2025Article
- Resting heart rate is associated with the prevalence of chronic kidney disease in Korean adult: the Korean National Health and Nutrition Survey.BMC public health · 2024Article
- Resting heart rate and the risk of incident type 2 diabetes mellitus among non-diabetic and prediabetic Iranian adults: Tehran lipid and glucose study.BMC public health · 2023Article
- Heart Rate Variability and Incident Type 2 Diabetes in General Population.The Journal of clinical endocrinology and metabolism · 2023Article
- Resting heart rate is a population-level biomarker of cardiorespiratory fitness: The Fenland Study.PloS one · 2023Article
- Admission Blood Glucose Level as a Predictor of Outcome in Intensive Care Patients: A Cross-Sectional Study.Cureus · 2022Article
- The predictive value of resting heart rate in identifying undiagnosed diabetes in Korean adults: Korea National Health and Nutrition Examination Survey.Epidemiology and health · 2022Article
- Increased resting heart rate and glucose metabolism in a community population.The Journal of international medical research · 2021Article
- Elevated resting heart rate as a predictor of inflammation and cardiovascular risk in healthy obese individuals.Scientific reports · 2021Article
- Association of Alk1 and Endoglin Polymorphisms with Cardiovascular Damage.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundPositive association between resting heart rate (RHR) and risk of type 2 diabetes (T2D) has been documented in several studies. However, whether RHR is an independent predictor of T2D and its potential interaction with other risk factors of T2D remain unclear.
methodsWe conducted a prospective cohort study of 31 156 men from the Health Professionals Follow-up Study (1992-2012). Cox proportional hazard model was used to examine the association between RHR and T2D risk. We further examined whether this association is modified by known risk factors. Lastly, we conducted a meta-analysis of prospective cohort studies.
resultsDuring 505 380 person-years of follow-up, we identified 2338 incident T2D cases. The multivariable-adjusted hazard ratio (HR) comparing the highest vs lowest categories of RHR was 1.69 (95% confidence interval [CI], 1.43-2.01). Increase in 10 bpm of RHR was associated with 19% increased risk of T2D in the fully adjusted model (HR, 1.19; 95% CI, 1.14-1.24). The HRs of T2D associated with RHR were stronger among those with normal weight or without hypertension (P interaction < 0.001). Moreover, RHR with other known risk factors cumulatively increased T2D risk. A meta-analysis consistently showed a positive association between RHR and T2D risk (the summary relative risk [RR] for highest vs lowest RHR, 1.53; 95% CI, 1.26-1.86, n = 12, the summary RR per 10 bpm increase, 1.17; 95% CI, 1.09-1.26, n = 13).
conclusionsHigh RHR was independently associated with increased risk of T2D. Our findings suggest that RHR, with other known risk factors, could be a useful tool to predict T2D risk.
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