ArticlePrenatal diagnosis2018
A study to assess global availability of fetal surgery for myelomeningocele.
Article in Prenatal diagnosis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Preclinical stem cell therapy in fetuses with myelomeningocele: A systematic review and meta-analysis.Prenatal diagnosis · 2021Pooled it
- The Evolution of Cephalocentesis in Contemporary Obstetric Practice: From Emergency Intervention to Planned Procedure.Fetal diagnosis and therapy · 2026Article
- Evolving Practices in Prenatal Open Spinal Dysraphism: A Global Survey of Selection Criteria, Surgical Techniques, and Diagnostic Trends.Prenatal diagnosis · 2026Article
- Maternal Folic Acid Supplement Use, Folate Intake, and Preterm Birth Among Infants With Spina Bifida.Birth defects research · 2025Article
- Effect of very preterm delivery on outcomes following in utero spina bifida repair.Pregnancy (Hoboken, N.J.) · 2025Article
- The Intrauterine Treatment of Open Spinal Dysraphism.Deutsches Arzteblatt international · 2025Review
- Position statement of Italian Society of Obesity (SIO): Gestational Obesity.Eating and weight disorders : EWD · 2024Review
- Prenatal Surgery for Open Fetal Spina Bifida in Patients with Obesity: A Review of Current Evidence and Future Directions.Journal of clinical medicine · 2024Review
- The Role of Social Determinants in Diagnosis Timing for Fetal Care Center-Eligible Conditions: A Scoping Review.Diagnostics (Basel, Switzerland) · 2024Article
- Fetal gene therapy.Journal of inherited metabolic disease · 2024Review
- Fetal Spina Bifida Repair in Obese Mothers: Is Maternal and Fetal Safety Compromised?Fetal diagnosis and therapy · 2024Article
- Development and Validation of a Scale to Measure Person-Centered Care in Fetal Care Centers.Fetal diagnosis and therapy · 2024Article
- Assessment of longitudinal brain development using super-resolution magnetic resonance imaging following fetal surgery for open spina bifida.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2023Article
- Trends in the early care of infants with myelomeningocele in the United States 2012-2018.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Global Policy and Practice for Intrauterine Fetal Resuscitation During Fetal Surgery for Open Spina Bifida Repair.JAMA network open · 2023Article
- Article
- 'We did everything we could'- a qualitative study exploring the acceptability of maternal-fetal surgery for spina bifida to parents.Prenatal diagnosis · 2021Article
- A Bibliographic Analysis of the Most Cited Articles in Global Neurosurgery.World neurosurgery · 2020Article
- Reference ranges for the fetal mesencephalon to occiput measurement at 11 to 13+6 weeks of gestation.Experimental and therapeutic medicine · 2020Article
- A study to assess knowledge and acceptability of foetal surgery for spina bifida amongst healthcare professionals in the UK.Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
aimTo establish the provision of fetal surgery for myelomeningocele (MMC) worldwide.
methodsThrough the International Society for Prenatal Diagnosis (ISPD) Fetal Therapy Special Interest Group and the North American Fetal Therapy Network (NAFTNet), fetal therapy centres were surveyed (September 2017-June 2018) regarding availability of fetal MMC surgical repair, patient inclusion criteria, repair techniques, number of cases, and outcome reporting. Responses were summarised on an interactive map on the ISPD website.
resultsForty-four of 59 centres responded (74.6%) of which 34 centres (77.1%) currently offered fetal surgery for MMC and seven centres (15.9%) were awaiting a first case after service set up. Patient inclusion criteria were similar and based on the Management of Myelomeningocele (MOMS) trial. Five centres (14.7%) operated beyond 26 weeks' gestational age, outside the MOMS criteria. Open fetal surgery was provided in 23 centres (67.6%), fetoscopic surgery only in five (14.7%), and six centres offered both types (17.6%). Neurosurgical closure was similar for open surgery but highly variable in fetoscopy surgery. The median number of cases per centre was 21 (range 1-253).
conclusionsFetal surgery for MMC is now offered globally. Two thirds of centres offer open repair via hysterotomy using criteria based on the MOMS trial.
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Registered trials
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